YOU ARE HERE : Endocrinology and Diabetes / : faculty : Mingyuan wu, md, phd- Assistant professor
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Mingyuan Wu, MD, PhD
Assistant Professor
wu
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Mailing Address:
941 Stanton L. Young Blvd., BSEB 330A
Oklahoma City, OK 73104-5020

Telephone:
(405) 271-3270
Fax:
(405) 271-3973
Email: mingyuan-wu@ouhsc.edu  

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Research Interests

  1. Mechanisms and predictors of pre-eclampsia in diabetic women.
  2. Involvement of modified low-density lipoprotein in diabetic retinopathy.
  3. Treatment of Chinese herbs in diabetic complications.

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Education

2003-2007 PhD - University of Oklahoma Health Sciences Center, OK
1999-2002 MS - Heilongjiang University of Chinese Medicine, PR China
1994-1999 MD - Heilongjiang University of Chinese Medicine, PR China

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Recent Publications
 

Basu A, Sanchez K, Leyva MJ, Wu M, Aston CE, and Lyons TJ. (2010). Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome. J Am Coll Nutr, in press.

Basu A, Sanchez K, Leyva MJ, Wu M, Aston CE, and Lyons TJ. (2010). Green Tea and Biomarkers of Inflammation in Obese Subjects with Metabolic Syndrome.  Nutrition.  in press.

Wu M, and Lyons TJ. (2010). Treatment approach to diabetes and dyslipidemia. Hormone Research, In Press.

Wu M, Chen Y, Wilson K, Boulton ME, Ma JX, Szweda LI, and Lyons TJ. (2009). Highly Oxidized, Glycated LDL Induced Apoptosis in Human Retinal Capillary Pericytes: Oxidative Stress, Proteasome Inhibition and Mitochondrial Dysfunction. Under revision in Diabetologia.

Gao J, Wu M*, Li L, Qin C, Farber JP, Linderoth B, and Foreman RD. (2010). Effects of spinal cord stimulation with “standard clinical” and higher frequencies on peripheral blood flow in rats. Brain Res. 1313:53-61

Dong Y, Zhang M, Wang S, Zhao Z, Chao L, Wu M, Choi HC, Lyons TJ, and Ming-Hui Zou MH. (2010).  Activation of AMP-activated Protein Kinase inhibits oxidized Low Density Lipoprotein-triggered Endoplasmic Reticulum (ER) stress and endothelium dysfunction in vivo.  Diabetes, In Press.

Qin C, Xiao L, Wu M, Farber JP, Linderoth B, and Foreman, RD. (2009). Modulation of neuronal activity in dorsal column nuclei by upper cervical spinal cord stimulation in rats. Neuroscience. 2009 164:770-6.

Chen Y, Hu Y, Zhou T, Zhou KK, Mott R, Wu M, Boulton M, Lyons TJ, Gao G, and Ma J-X. (2009). Activation of Wnt Pathway Plays a Pathogenic Role in Diabetic Retinopathy in Humans and Animal Models. American Journal of Pathology, 175(6):2676-85.

Wu M, Chen Y, Wilson K, Chirindel A, Ihnat M, Yu Y, Boulton ME, Szweda LI, Ma JX, and Lyons TJ. (2008). Intra-retinal Leakage and Oxidation of LDL in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 49(6):2679-85.

Dong Y, Wu Y, Wu M, Wang S, Zhang J, Xie Z, Xu J, Song P, Wilson K, Zhao Z, Lyons TJ, and Zou MH. (2008). Activation of the calcium-dependent µ-Calpain by oxidized and glycated LDL triggers the degradation of endothelial nitric oxide synthase. Journal of Cellular and Molecular medicine. [Epub ahead of print].

Sun Z, Li X, Su Z, Zhao Y, Zhang Y, and Wu M*. (2009). Electro-acupuncture Enhanced Differentiation of Bone Marrow Stromal Cells into Neuronal Cells in Rats with Spinal Cord Injury. Journal of Sport Rehabilitation 18:398-406.

Diffley JM, Wu M, (co-first author) Sohn M, Song W, Hammad SM, and Lyons TJ. (2009). Induction of Apoptosis by Oxidized Glycated Low-Density Lipoproteins in Human Retinal Capillary Pericytes is Independent of Activation of MAPK Signaling Pathways. Molecular Vision. 15:135-45.

Qin C, Thorkilsen ML, Wu M, Farber JP, Ma JX, and Foreman RD. (2009). Characterization of upper thoracic spinal neurons responding to esophageal distention in diabetic rats. Autonomic Neuroscience Basic and Clinical. 145(1-2):27-34.

Wu M*, Komori N, Qin C, Farber JP, Linderoth B, and Foreman RD. (2008). Spinal cord stimulation-induced vasodilation: roles of ERK and AKT pathways. Brain Research. 1207:73-83.

Wu M*, Linderoth B, and Foreman RD. (2008). Putative mechanisms behind effects of spinal cord stimulation on vascular diseases: a review of experimental studies. Autonomic Neuroscience Basic and Clinical. 138: 9-23.

Xiao L, Farber JP, Wu M, Foreman RD, and Qin C. (2008). Role of TRPV1 in Augmentation of Cerebral Blood Flow by Cervical Spinal Cord Stimulation in Rats. Neuroscience. 152, 950-958.

Chen J, Wu M, Sezate SA, and McGinnis JF.(2008). Molecular Participants of Light-Dependent Rod Alpha-Transducin Translocation. Jounral of Neurochemistry. 104,1280-1292.

Wu M*, Qin C, Foreman RD, and Farber JP. (2007). Transient receptor potential vanilloid receptor-1 does not contribute to slowly adapting airway receptor activation by ammonia. Autonomic Neuroscience: Basic and Clinical. 133: 121-127.

Wu M*, Thorkilsen M, Qin C, Farber JP, Linderoth B, and Foreman RD. (2007). Effects of spinal cord stimulation on peripheral circulation in stretozotocin-induced diabetic rats. Neuromodulation. 10: 217-223.

Wu M*, Qin C, Farber JP, Linderoth B, and Foreman RD. (2007). Roles of peripheral terminals of transient receptor potential vanilloid-1 containing sensory fibers in spinal cord stimulation-induced peripheral vasodilation. Brain Research. 1156: 80-92.

Chen J, Wu M, Sezate SA, and McGinnis JF. (2007). Light Induced Cone Alpha-Transducin Translocation. Invest. Ophthalmol. Vis. Sci. 48: 3350-3355.

Wu M*, Komori N, Qin C, Farber JP, Linderoth B, and Foreman RD. (2006). Sensory fibers containing vanilloid receptor-1(VR-1) mediate spinal cord stimulation-induced vasodilation. Brain Research. 1107: 177-184.

Reviews and Invited Papers
 

Wu M*, Linderoth B, and Foreman RD. (2008). Putative mechanisms behind effects of spinal cord stimulation on vascular diseases: a review of experimental studies. Autonomic Neuroscience Basic and Clinical. 138: 9-23.

*Corresponding author

 

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