Shuangxi Wang, MD, PhD Post-Doctoral Fellow
Mailing Address: 941 Stanton L. Young Blvd., BSEB 315 Oklahoma City, OK 73104	Telephone: (405) 271-5896 ext 48466 Fax: (405) 271-3973
Email: shuangxi-wang@ouhsc.edu

Research Interests

1. The mechanism and role of endothelial dysfunction in diabetic vascular complications.

Education

Wang S , Jian Xu, Ping Song, Yong Wu, Ming-Hui Zou. Acute Inhibition of GTP Cyclohydrolase 1 Uncouples Endothelial Nitric Oxide Synthase and Elevates Systolic Blood Pressure. Hypertension. 2008, in press.

Xu Jian, Wu Yong, Song Ping, Zhang Miao, Wang S, Zou Minghui. Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus. Circulation. 2007; 116(8):944-953.

Wang SX, Sun XY, Zhang XH, et al. Cariporide inhibits high glucose-mediated adhesion of monocyte-endothelial cell and expression of intercellular adhesion molecule-1. Life Sci. Apr 25, 2006.

Wang S , Jian Xu, Ping Song, Yong Wu, and Minghui Zou. Endothelial Dysfunction in AMP-activated Kinase α2 Knockout Mice: Role of NAD(P)H oxidase-derived Superoxide Anions. Circulation, Oct 2007; 116: II_232. (abstract)

Jian Xu, Wang S , Yong Wu, Ping Song, Miao Zhang, and Ming-Hui Zou. Oxidative Stress Induces Endothelial Dysfunction: Role of Ubiquitin-Proteasome System. Circulation, Oct 2007; 116: II_31.(abstract)