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Shujie Yu, MD
Research Associate

Mailing Address:
941 Stanton L. Young Blvd., BSEB
Oklahoma City, OK 73104

(405) 271-8001 x52604
(405) 271-3973


Research Interests

  1. Diabetes-induced protein post-translational modifications.
  2. The role of 26S proteasomes in coronary heart disease.



2009 - Present PhD candidate - Cardiology, Sun Yat-sen University, Guangzhou, China
2004 MS - Cardiology, Sun Yat-sen University, Guangzhou, China
2001 MD - Clinical Medicine, College of Medicine, Zhengzhou University, Zhengzhou, China


Recent Publications

Liu H, Yu S, Zhang H and Xu J. (2012). Angiogenesis impairment in diabetes: Role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2. PLoS ONE.  (Accepted).

Liu H, Yu S, Xu W and Xu J. (2012). Enhancement of 26S proteasome functionality connects oxidative stress and vascular endothelial inflammatory response in diabetes. Arteriosclerosis, Thrombosis, and Vascular Biology. 32 (9):2131-2140. PMID: 22772755.

Yu SJ, Chen L, Zhao CL, Liu JL, Wu Z, et al. (2006). Relationship of the level of serum amyloid A with obesity. New Chinese Medicine, 37(3), 162-164.

Liu ZY, Liang CQ, Yu SJ, Zhao F, et al. (2006). The levels of serum amyloid A among an aged population. Lingnan Journal of Emergency Medicine, 11(3), 174-175.

Yu SJ, Chen L, Liu JL, et al. (2005). The correlatives study of the serum A levels and coronary heart disease. South China Journal of Cardiovascular Disease, 11(4), 252-255.

Chen L, Yu SJ, Zhao CL, Liu JL, Zhou HJ, Peng CQ, et al. (2005). Relationship of the level of serum amyloid A with athletic sports and smoking in middle aged and elderly people. Chinese Journal of Clinical Rehabilitation, 2005, 9(47), 14-16.



Liu HT, Yu SJ, and Xu J. (2012). Autophagy-mediated Reduction of Vascular Endothelial Growth Factor Receptor 2 Impairs Diabetic Angiogenesis. American Diabetes Association's 72nd Scientific Sessions, June 8−12, 2012, Philadelphia, Pennsylvania.

Liu HT, Yu SJ, and Xu J. (2011). Hyperglycemia induced 26S proteasome activation is an early event in streptozotocin−treated mice. American Diabetes Association's 71st Scientific Sessions, June 24−28, 2011, San Diego, California (this abstract has also been selected to be showcased in a Guided Audio Poster Tour).

Liu HT, Yu SJ and Xu J.* (2011). Hyperglycemia activates 26S proteasome in STZ-treated mice. Central Region IDEA Conference. Omaha, NE, May 23-25, 2011. (*Corresponding author and selected as an oral presentation).



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The University of Oklahoma Health Sciences Center

Endocrinology and Diabetes
1000 N. Lincoln Blvd.; Harold Hamm Diabetes Center Building #2900
Oklahoma City, OK 73104
Phone - (405) 271-5896
FAX - (405) 271-7522

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