Other Compliance Offices:
inc_menu_main.asp
  OUHSC IACUC Home
  Program Contacts
Protocol Review Process
  Forms
  Policies Procedures Guidelines
  Occupational Health Program
  IACUC Members Only
  Training
Report Concerns and Misconduct
  Database Searches
  Campus Links:
 

OUHSC

 

Comparative Medicine

DATABASE SEARCHES

The IACUC is tasked to determine that... "The principal investigator has considered alternatives to procedures that may cause more than momentary or slight pain or distress to the animals, and has provided a written narrative description of the methods and sources, e.g., the Animal Welfare Information Center, used to determine that alternatives were not available."  (9CFR, Part 2, Sec. 2.31 (d) (1) (ii))

There are two distinct purposes for the database search, both of which are important to satisfy requirements of the Public Health Service Policy, the Animal Welfare Act, and Policy #12 of the Animal Care and Resource Guide:

1) To ensure that there are no scientifically viable alternatives to the use of animals

2) To ensure that the proposed study does not unnecessarily duplicate previous work .

Both requirements must be met before IACUC approval can be obtained.

 

When submitting a protocol request to the IACUC, the narrative of the database search must include the names of the databases used, the date the search was performed, the time period covered in the search, and the search strategy.

 

At least two independent databases must be searched. Searches of the PubMed database automatically include Medline as one of the data sources and therefore Medline is not an independent database and does not fulfill the requirement for searching two databases if PubMed is used as one of the databases.

The Robert M. Bird Health Sciences Library webpage also contains helpful resources for completing the database search requirements.

 

Tips on searching for animal alternatives can also be viewed here: 2005 Database Search Presentation

 

 

 

 

 

Institutional Animal Care and Use Committee (IACUC)
Biomedical Sciences Building - Room 101
(405) 271-7381

On Campus Mailing Address:
IACUC Office - BMSB 101


This web site Designed and Built by Information Design Services a department of the University of Oklahoma Health Sciences Center.

Every effort will be made to update the information contained on these pages as necessary. However, it is the responsibility of the user to determine that he or she is relying on the most current version of any particular information. Any questions about the material should be directed to the referenced office or department.
    
Copyright © 2003 The Board of Regents of the University of Oklahoma, All Rights Reserved.
Disclaimer | Copyright