Molluscum contagiosum is an infection of a member of the pox virus resulting in waxy, umbilicated raised lesions of the skin. Toxic debris from the lesion as cells lysis can result in a follicular conjunctivitis. Histologically (1,2) there is a center crater with cells swollen with viral inclusions. As the cells migrate from the basement membrane to the surface, they fills with the virus, causing distention and a more eosinophilic appearance. The cells then lysis and release the virus to spread to surrounding areas. Children and immunosuppressed individuals are more susceptible to these lesions. Back to Eyelid