Sebaceous cell carcinoma arise from the meibomian glands, glands of Zeiss and sebaceous glands of the caruncle. These tumors may mimic a chronic chalzion or blepharoconjunctivitis that is unresponsive to treatment. The skin may have areas of yellow due to lipid deposition. The tumor is highly aggressive and may be multicentric. It can display several different patterns of growth. The cell's cytoplasm is foamy in appearance and stains for lipid (1). The nuclei are pyknotic and mitotic figures can be seen. Back to Eyelid