Key Areas of Growth in Biotech Industry

1. Pharmacogenomics


* Human Genome Project (analysis of DNA for function of discovered genes)


* Single Nucleotide Polymorphisms (mutations involved in disease and health


* individualized medicine with therapies according to patient's genetics


2. Recombinant-Based Therapies


* recombinant protein (proteins made in a foreign or heterologous host)


* sustained delivery formulations (goal of once a day or month medicines)


* plant-based production of pharmaceutical proteins


* consumer market (buy in Walmart) - especially cardiovascular drugs / therapies


3. Small-Molecule Drugs


* combinatorial chemistry


* mapping of active sites / modeling of proteins


4. Genetic Modification


* genetic diagnosis


* gene switching / therapy


* eliminate "nuisance" conditions


5. DNA Typing


* criminology / anthropology


* wildlife management and anti-poaching


6. Cloning


* tissue engineering / generation of replacement organs


7. Anti-Aging


* gene therapy


* metabolic pathway alteration


8. Bioinformatics / Computer Simulation


* annotation of genomes (define function of genes)


* predictive models (metabolism & interactions during health & disease)


* DNA arrays / microfluidics technology heavily interfaced to computers and automation


9. Agriculture


* genetically enhanced or modified crops


* reduction of pesticide / herbicide use


* alter "output traits" (flavor, nutrition)


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