|
Database for Drug – Induced Thrombocytopenia from Group Patient
Reports: An Update
|
||||||||
|
Total TCP= Total number of patients with thrombocytopenia |
||||||||
|
Ex TCP= The number of people in the experimental group that
developed thrombocytopenia |
||||||||
|
Ct TCP=The number of people in the control group that developed
thrombocytopenia |
||||||||
|
Drug name |
CITATION |
YR |
AGE |
TOTAL TCP |
EX_TCP |
CT_TCP |
SCORE |
EXCLUSION |
|
ABCIXIMAB |
CIRCULATION 89:596-603 |
1994 |
Adult |
|
|
|
5 |
1 |
|
ABCIXIMAB |
NEJM 330:956-961 |
1994 |
Adult |
86 |
62 |
24 |
4 |
NA |
|
ABCIXIMAB |
LANCET 349:1429-1435 |
1997 |
Adult |
36 |
29 |
7 |
1 |
NA |
|
ABCIXIMAB |
NEJM 336:1689-1696 |
1997 |
Adult |
16 |
12 |
4 |
4 |
NA |
|
ABCIXIMAB |
J AM COLL CARDIOL 31:55A |
1998 |
Unknown |
6 |
6 |
|
3 |
NA |
|
ABCIXIMAB |
CATHETER CARDIOVASC INTERV 47:294-296 |
1999 |
Adult |
1 |
1 |
|
3 |
NA |
|
ABCIXIMAB |
CIRCULATION 104:870-875 |
2001 |
Adult |
23 |
23 |
0 |
3 |
NA |
|
ABCIXIMAB |
LANCET 357:1905-1914 |
2001 |
Adult |
298 |
243 |
55 |
1 |
NA |
|
ABCIXIMAB |
LANCET 357:1915-1924 |
2001 |
Adult |
331 |
305 |
26 |
1 |
NA |
|
ABCIXIMAB |
NEJM 344:1888-1894 |
2001 |
Adult |
102 |
16 |
86 |
1 |
NA |
|
ABCIXIMAB |
ANN HEMATOL 81:76-79 |
2002 |
Adult |
8 |
|
|
3 |
NA |
|
ABCIXIMAB |
AM J CARDIOL 93:453-455 |
2004 |
Adult |
11 |
0 |
11 |
2 |
NA |
|
ABCIXIMAB |
CARDIOL 102:184-187 |
2004 |
Adult |
28 |
28 |
|
3 |
NA |
|
ABCIXIMAB |
CIRCULATION 109:2203-2206 |
2004 |
Adult |
99 |
57 |
12 |
1 |
NA |
|
ABCIXIMAB |
CIRCULATION 109:2203-6 |
2004 |
Adult |
|
58 |
12 |
1 |
NA |
|
ABCIXIMAB |
THROMB HAEMOST 92:820-8 |
2004 |
Adult |
6 |
|
|
3 |
NA |
|
ABCIXIMAB |
J INTERV CARDIOL 18:33-37 |
2005 |
Adult |
13 |
13 |
|
3 |
NA |
|
ABCIXIMAB |
AM J CARDIOL 97:426-9 |
2006 |
Adult |
|
|
|
5 |
1 |
|
ABCIXIMAB |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
ACENOCOUMAROL |
CLIN APPL THROMB HEMOST 8:213-215 |
2002 |
Both |
|
|
|
5 |
1 |
|
ACETAMINOPHEN |
BLOOD 82: 2714-2718 |
1993 |
Adult |
10 |
|
|
4 |
NA |
|
ACETYLDIGOXIN |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
ADALIMUMAB |
J DRUGS DERMATOL 10:280-4 |
2011 |
Adult |
|
|
|
5 |
1 |
|
ALEMTUZUMAB |
N ENGL J MED 359:1786-801 |
2008 |
Pediatric |
|
6 |
1 |
5 |
5 |
|
ALEMTUZUMAB |
BLOOD 118:6299-305 |
2011 |
Adult |
|
|
|
5 |
5 |
|
ALFACALCIDOL |
LEUK RES 34: 1151-7 |
2010 |
Adult |
|
|
|
5 |
1, 7 |
|
ALLOPURINOL |
CLIN RHEUMATOL 19:180-6 |
2013 |
|
|
|
|
5 |
1 |
|
ALTEPLASE |
J AM COLL CARDIOL 11:1-11 |
1988 |
Unknown |
|
|
|
5 |
1 |
|
ALTEPLASE |
J AM COLL CARDIOL
23:891-898 |
1994 |
Adult |
|
|
|
5 |
1 |
|
AMPHOTERICIN B |
AM J DIS CHILD 133:731-4 |
1979 |
Both |
|
|
|
5 |
1 |
|
ANTITHYMOCYTE GLOBULIN |
DIABETES RES 2:271-6 |
1985 |
Pediatric |
3 |
3 |
0 |
5 |
7 |
|
ANTITHYMOCYTE GLOBULIN |
AM J HEALTH SYST PHARM 68:2276-82 |
2011 |
|
|
|
|
5 |
1 |
|
ARGATROBAN |
ANN THORAC SURG 85:1651-5 |
2008 |
Adult |
16 |
80 |
|
3 |
NA |
|
ARGATROBAN |
J THROMB THROMBOLYSIS 29:1-7 |
2010 |
Adult |
|
|
|
5 |
1 |
|
ARGATROBAN |
PEDIATR BLOOD CANCER 56:1103-9 |
2011 |
Pediatric |
|
|
|
5 |
3 |
|
ASPIRIN |
ANN RHEUM DIS 22:440-443 |
1963 |
Unknown |
|
|
|
5 |
1 |
|
AT G-F; FRESENIUS (LYMPHOGLOBULIN) |
EXP CLIN TRANSPLANT 2:178-82 |
2004 |
Adult |
|
|
|
5 |
3 |
|
ATENOLOL |
BLOOD 82:2714-2718 |
1993 |
Adult |
4 |
|
|
4 |
NA |
|
AZATHIOPRINE |
GUT 34:1081-5 |
1993 |
Adult |
15 |
|
|
3 |
NA |
|
AZATHIOPRINE |
ALIMENT PHARMACOL THER 25:941-7 |
2007 |
Pediatric |
|
|
|
4 |
NA |
|
BIVALIRUDIN |
AM HEART J 161:298-306 |
2011 |
Adult |
98 |
98 |
|
3 |
NA |
|
BORTEZOMIB |
BLOOD 106:3777-3784 |
2005 |
Adult |
68 |
68 |
|
5 |
3 |
|
BRENTUXIMAB VEDOTIN |
CLIN CANCER RES 18: 5845-9 |
2012 |
|
|
|
|
3 |
3 |
|
CAPECITABINE |
INT J MED SCI 9: 33-9 |
2012 |
|
|
|
|
5 |
3 |
|
CAPTOPRIL |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
CARBAMAZEPINE |
AM J PSYCHIATRY 142: 1196-1199 |
1985 |
Adult |
1 |
1 |
0 |
5 |
6 |
|
CARBAMAZEPINE |
AM J PSYCHIATRY 152:413-418 |
1995 |
Pediatric |
1 |
|
|
5 |
1 |
|
CARBAMAZEPINE |
NEUROL INDIA 51:427 |
2003 |
Pediatric |
|
|
|
5 |
1 |
|
CARBOPLATIN |
ANN PHARMACOTHER 43:235-41 |
2009 |
|
|
|
|
5 |
3 |
|
CARFILZOMIB |
Clin Cancer Res 19: 4559-63 |
2013 |
|
|
|
|
3 |
3 |
|
CARFILZOMIB |
J Oncol Pharm Pract
19: 348-54 |
2013 |
|
|
|
|
3 |
3 |
|
CEFTRIAXONE |
AM J DIS CHILD 137:1048-51 |
1983 |
Pediatric |
|
|
|
5 |
1 |
|
CEPHALEXIN |
SCAND J INFECT DIS 2:53-8 |
1970 |
Both |
|
|
|
5 |
1 |
|
CHLORTHALIDONE |
ACTA MED SCAND 183:245-50 |
1968 |
Both |
14 |
|
|
5 |
1 |
|
CILASTATIN/IMIPENEM |
REV INFECT DIS 7: 5471-5475 |
1985 |
Adult |
2 |
|
|
5 |
1 |
|
CILASTATIN/IMIPENEM |
PHARMACOTHERAPY 19:108-113 |
1999 |
Adult |
7 |
4 |
3 |
2 |
NA |
|
CLOPIDOGREL |
CATHETER CARDIOVASC INTERV 50:426-30 |
2000 |
Adult |
16 |
11 |
5 |
2 |
NA |
|
CYCLOCYTIDINE |
CANCER TREAT REP 60:215-6 |
1976 |
Pediatric |
|
|
|
5 |
1,3 |
|
DACTINOMYCIN/ ACTINOMYCIN |
J PEDIATRICS 107: 611-614 |
1985 |
Pediatric |
|
|
|
5 |
3 |
|
DACTINOMYCIN/ ACTINOMYCIN |
MED PEDIATR ONCOL 41:483-485 |
2003 |
Pediatric |
29 |
|
|
1 |
NA |
|
DEFERASIROX |
ANN TROP PAEDIATR |
2011 |
Both |
6 |
|
|
4 |
NA |
|
DEFERIPRONE |
J PAEDIATR CHILD HEALTH 47:812-7 |
2011 |
Both |
9 |
|
|
5 |
1 |
|
DIFLUNISAL |
CURR MED RES OPIN 9:568-77 |
1985 |
Adult |
|
|
|
5 |
1 |
|
DIGOXIN |
BLOOD 82: 2714-2718 |
1993 |
Adult |
9 |
|
|
4 |
NA |
|
DIGOXIN |
BLOOD 82:2714-2718 |
1993 |
Adult |
9 |
|
|
2 |
NA |
|
DIPHTHERIA/TETANUS/PERTUSSIS VACCINE |
PEDIATR INFECT DIS J 22:119-122 |
2003 |
Pediatric |
8 |
|
|
3 |
NA |
|
DIPYRIDAMOLE |
BLOOD 82: 2714-2718 |
1993 |
Adult |
8 |
|
|
2 |
NA |
|
DIPYRIDAMOLE |
BLOOD 82:2714-2718 |
1993 |
Adult |
8 |
|
|
2 |
NA |
|
DROSPIRENONE/ETHINYLESTRADIOL |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
EFALIZUMAB (RAPTIVA) |
J DRUGS DERMATOL 10:280-4 |
2011 |
Adult |
|
|
|
5 |
1 |
|
EPOETIN ALFA |
AM J GASTROENTEROL 101:2275-82 |
2006 |
Adult |
|
|
|
5 |
2 |
|
EPOPROSTENOL |
CHEST 135:130-6 |
2009 |
|
|
|
|
5 |
1 |
|
EPTIFIBATIDE |
CIRCULATION 91:2151-2157 |
1995 |
Adult |
2 |
2 |
0 |
4 |
NA |
|
EPTIFIBATIDE |
CIRCULATION 95:846-854 |
1997 |
Adult |
19 |
14 |
5 |
4 |
NA |
|
EPTIFIBATIDE |
LANCET 349:1422-1428 |
1997 |
Adult |
114 |
79 |
35 |
4 |
NA |
|
EPTIFIBATIDE |
NEJM 339:436-443 |
1998 |
Adult |
635 |
318 |
317 |
1 |
NA |
|
EPTIFIBATIDE |
CIRCULATION 99:2892-2900 |
1999 |
Adult |
454 |
227 |
227 |
4 |
NA |
|
EPTIFIBATIDE |
LANCET 356:2037-2044 |
2000 |
Adult |
2 |
2 |
0 |
4 |
NA |
|
EPTIFIBATIDE |
J AM COLL CARDIOL 39:377-386 |
2002 |
Adult |
13 |
15 |
0 |
1 |
NA |
|
FAMOTIDINE |
J NEUROSURG ANESTHESIOL 16:291-293 |
2004 |
Adult |
28 |
17 |
11 |
2 |
NA |
|
FILGRASTIM (GRANULOCYTE COLONY STIMULATING FACTOR (G-CSF)) |
BLOOD 87:4916-7 |
1996 |
Adult |
|
|
|
5 |
5 |
|
FILGRASTIM (GRANULOCYTE COLONY STIMULATING FACTOR (G-CSF)) |
BLOOD 96:2049-54 |
2000 |
Both |
|
|
|
5 |
5 |
|
FLUCONAZOLE |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
FLUOROURACIL |
INT J MED SCI 9: 33-9 |
2012 |
|
|
|
|
5 |
3 |
|
FUROSEMIDE |
BLOOD 82: 2714-2718 |
1993 |
Adult |
6 |
|
|
4 |
NA |
|
FUROSEMIDE |
BLOOD 82:2714-2718 |
1993 |
Adult |
6 |
|
|
2 |
NA |
|
FUSIDIC ACID |
INT J ANTIMICROB AGENTS 2:S3-9 |
1999 |
Unknown |
|
|
|
5 |
1 |
|
GANCICLOVIR |
BLOOD 99:1159-1164 |
2002 |
Both |
|
|
|
5 |
1 |
|
GEMCITABINE |
CLIN ONCOL 18:639 |
2006 |
Adult |
|
|
|
5 |
3 |
|
GENTAMICIN |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
GlYCOPROTEIN IIb/IIIa INHIBITOR |
J AM COLL CARDIOL 57:1200-1 |
2011 |
Adult |
|
|
|
5 |
1 |
|
GOLD |
ARTHRITIS RHEUM 22:495-501 |
1979 |
Both |
7 |
|
|
5 |
1 |
|
GOLD |
SEMIN ARTHRITIS RHEUM 14:238-46 |
1985 |
Both |
11 |
|
|
5 |
1 |
|
HEPATITIS A VACCINE |
LANCET 345:1638 |
1995 |
Adult |
|
|
|
3 |
NA |
|
HEPATITIS B VACCINE |
LANCET 345:1638 |
1995 |
Adult |
8 |
|
|
3 |
NA |
|
HEPATITIS B VACCINE |
SCAND J INFECT DIS 30:115-8 |
1998 |
Pediatric |
7 |
|
|
1 |
NA |
|
HEPATITIS B VACCINE |
PEDIATR INFECT DIS J 22:119-122 |
2003 |
Pediatric |
3 |
|
|
3 |
NA |
|
HYDROCHLOROTHIAZIDE |
J PEDIATR 77:1097-8 |
1970 |
Pediatric |
0 |
|
|
5 |
1 |
|
HYDROCHLOROTHIAZIDE/TRIAMTERENE |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
HYDROXYCHLOROQUINE |
ANN RHEUM DIS 22:440-443 |
1963 |
Unknown |
|
|
|
5 |
1 |
|
IBUPROFEN |
PEDIATRICS 115:1529-35 |
2005 |
Pediatric |
|
|
|
4 |
NA |
|
INAMRINONE |
CLIN PHARMACOL THER 53:661-7 |
1993 |
Pediatric |
8 |
|
|
2 |
NA |
|
INFLUENZA VACCINE |
PEDIATR INFECT DIS J 22:119-122 |
2003 |
Pediatric |
2 |
|
|
3 |
NA |
|
INFLUENZA VACCINE |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
INTEGRILIN |
CIRCULATION 91: 2151-2157 |
1995 |
Adult |
3 |
3 |
0 |
4 |
NA |
|
INTERFERON ALPHA |
HAEMATOLOGICA 85:63-6 |
2000 |
Adult |
|
|
|
5 |
1 |
|
INTERFERON ALPHA |
J HEPATOL 32:1041-1042 |
2000 |
Unknown |
|
|
|
5 |
2,7 |
|
INTERFERON ALPHA |
J MED VIROL 64:460-5 |
2001 |
Adult |
|
|
|
5 |
1 |
|
LENALIDOMIDE |
BR J HAEMATOL 138"640-3 |
2007 |
Adult |
|
|
|
5 |
3,7 |
|
LEVETIRACETAM |
J CHILD NEUROL 25: 551-5 |
2009 |
Pediatric |
|
|
|
5 |
1 |
|
LEVETIRACETAM |
EPILEPSIA 51(12):2492-5 |
2010 |
Adult |
29 |
|
|
5 |
1 |
|
LINEZOLID |
MED LETT DRUGS THER 42:45-46 |
2000 |
NA |
|
|
|
5 |
1,3 |
|
LINEZOLID |
PHARMACOTHERAPY 21:1010-1013 |
2001 |
Unknown |
|
|
|
5 |
1,3 |
|
LINEZOLID |
ANTIMICROB AGENTS CHEMOTHER 46:2723-2726 |
2002 |
Adult |
|
|
|
5 |
1,3 |
|
LINEZOLID |
CID 34:695-698 |
2002 |
Adult |
6 |
|
|
5 |
3 |
|
LINEZOLID |
CID 35:348-349 |
2002 |
Adult |
9 |
|
|
5 |
3 |
|
LINEZOLID |
CLIN INFECT DIS 34:695-698 |
2002 |
Adult |
6 |
|
|
5 |
3 |
|
LINEZOLID |
INFECT DIS CLIN PRAC 11:198-204 |
2002 |
Adult |
|
|
|
5 |
1,3 |
|
LINEZOLID |
CID 36:159-168 |
2003 |
Both |
|
|
|
5 |
1,3 |
|
LINEZOLID |
CID 37:1609-1616 |
2003 |
Adult |
16 |
8 |
8 |
5 |
3 |
|
LINEZOLID |
CLIN THER 25:980-982 |
2003 |
Adult |
|
|
|
5 |
1,3 |
|
LINEZOLID |
PEDIATR INFECT DIS J 22:S186-92 |
2003 |
Pediatric |
12 |
10 |
2 |
5 |
3 |
|
LINEZOLID |
CID 38:1058-1064 |
2004 |
Adult |
4 |
3 |
1 |
5 |
3 |
|
LINEZOLID |
CLINCAL INFECTIOUS DIS 38:1058-1064 |
2004 |
Adult |
18 |
7 |
11 |
5 |
3 |
|
LINEZOLID |
J ANTIMICROB CHEMOTHER 6:440 |
2005 |
Adult |
12 |
12 |
|
5 |
3 |
|
LINEZOLID |
CID 42:66-72 |
2006 |
Adult |
49 |
79 |
43 |
5 |
3 |
|
LINEZOLID |
INT J ANTIMICROB AGENTS 28:345-51 |
2006 |
Adult |
27 |
65 |
22 |
5 |
3 |
|
LINEZOLID |
CLIN THER 31:2126-33 |
2009 |
Adult |
7 |
|
|
5 |
3 |
|
LINEZOLID |
INT J ANTIMICROB AGENTS 33:92-3 |
2009 |
Adult |
|
|
|
5 |
1,3 |
|
LINEZOLID |
INT J ANTIMICROB AGENTS 36:179-81 |
2010 |
Adult |
|
|
|
5 |
3 |
|
MEASLES VACCINE |
NEJM 275:352-356 |
1966 |
Both |
22 |
22 |
0 |
5 |
1,5 |
|
MEASLES VACCINE |
PEDIATR INFECT DIS J 15:88-90 |
1996 |
Both |
56 |
|
|
5 |
5 |
|
MEASLES VACCINE |
PEDIATR INFECT DIS J 22:S186-S192 |
2003 |
Pediatric |
2 |
|
|
5 |
5 |
|
MEASLES, MUMPS, RUBELLA VACCINE (MMR VACCINE) |
PEDIATR INFECT DIS J 15:44-48 |
1996 |
Pediatric |
54 |
|
|
5 |
5 |
|
MEASLES, MUMPS, RUBELLA VACCINE (MMR VACCINE) |
ARCH DIS CHILD 84:227-229 |
2001 |
Pediatric |
28 |
|
|
5 |
5,7 |
|
MEASLES, MUMPS, RUBELLA VACCINE (MMR VACCINE) |
PEDIATR INFECT DIS J 22:119-122 |
2003 |
Pediatric |
46 |
|
|
5 |
5 |
|
MEASLES, MUMPS, RUBELLA VACCINE (MMR VACCINE) |
VACCINE 29:1319-23 |
2011 |
Adult |
|
|
|
5 |
1,5 |
|
MELPERONE |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
MENATETRENONE |
LEUK RES 34: 1151-7 |
2010 |
Adult |
|
|
|
5 |
1, 7 |
|
MEROPENEM |
CLIN INFECT DIS 24:S222-30 |
1997 |
Adult |
|
11 |
11 |
5 |
1 |
|
MEROPENEM |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
METHOTREXATE |
BRIT J CANCER 22: 244-249 |
1968 |
NA |
|
|
|
5 |
3 |
|
METOPROLOL |
BLOOD 82:2714-2718 |
1993 |
Adult |
2 |
|
|
4 |
NA |
|
MOLSIDOMINE |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
NATALIZUMAB |
JAMA NEUROL 71: 891-5 |
2014 |
Both |
|
|
|
5 |
1 |
|
NEDAPLATIN |
EUR J GYNAECOL ONCOL 31:517-21 |
2010 |
Adult |
|
|
|
5 |
3 |
|
NICOTINAMIDE |
KIDNEY INT 68:2911-2912 |
2005 |
|
|
|
|
5 |
2 |
|
NICOTINAMIDE |
NEFROLOGIA 31:58-65 |
2011 |
Adult |
|
|
|
4 |
NA |
|
NITROFURANTION |
ARCH INTERN MED
128:399-404 |
1971 |
Both |
|
|
|
5 |
1 |
|
PANTOPRAZOLE |
EXPERT OPIN PHARMACOTHER 8:2025-28 |
2007 |
Adult |
|
|
|
4 |
NA |
|
PEGINTERFERON ALFA 2B |
CLEVE CLIN J MED 71:S17-S21 |
2004 |
|
|
|
|
5 |
1 |
|
PEGINTERFERON ALFA 2B/RIBAVIRIN |
LANCET 358:958-965 |
2001 |
Adult |
|
|
|
5 |
1 |
|
PEGINTERFERON ALFA 2B/RIBAVIRIN |
NEJM 347:975-982 |
2002 |
Adult |
|
|
|
5 |
1 |
|
PEGINTERFERON ALFA 2B/RIBAVIRIN |
PHARMACOEPIDEMIOL DRUG SAF 23: 480-8 |
2014 |
|
|
|
|
5 |
1 |
|
PENICILLAMINE |
AUST N Z J MED 9:495-503 |
1979 |
Adult |
7 |
7 |
|
5 |
3 |
|
PENICILLAMINE |
ARTHRITIS RHEUM 23:158-64 |
1980 |
Adult |
|
|
|
5 |
3 |
|
PENICILLAMINE |
J PEDIATR 112:799-804 |
1988 |
Pediatric |
0 |
0 |
0 |
5 |
2,3 |
|
PENICILLAMINE |
ANN PHARMACOTHER 34:15-8 |
2000 |
Pediatric |
0 |
|
|
5 |
2,3 |
|
PHENYTOIN |
PHARMACOTHERAPY 19:108-113 |
1999 |
Adult |
14 |
5 |
9 |
2 |
NA |
|
PIPERACILLIN |
PHARMACOTHERAPY 19:108-113 |
1999 |
Adult |
12 |
5 |
7 |
2 |
NA |
|
PNEUMOCOCCAL VACCINE |
JAMA 292:1702-10 |
2004 |
Pediatric |
12 |
|
|
5 |
1 |
|
PORCINE FACTOR VIII |
THROMB HAEMOST 65:245-7 |
1991 |
Both |
|
|
|
5 |
4 |
|
PROPRANOLOL |
BLOOD 82:2714-2718 |
1993 |
Adult |
4 |
|
|
4 |
NA |
|
QI-SUPPLEMENTING/YIN-NOURISHING THERAPY |
J TRADIT CHIN MED 31:277-81 |
2011 |
Both |
|
|
|
5 |
1 |
|
QUININE |
BLOOD 82:2714-2718 |
1993 |
Adult |
14 |
|
|
2 |
NA |
|
QUININE |
AM J HEMATOL 70:313-317 |
2002 |
Both |
|
|
|
5 |
1 |
|
RIFAMPIN |
BR MED J 3:343-7 |
1971 |
Both |
3 |
|
|
5 |
1 |
|
RIFAMPIN |
POSTGRAD MED J 47:742-747 |
1971 |
Both |
3 |
|
|
5 |
1 |
|
RIFAMPIN |
SCAND J RESPIR DIS SUPPL 84:119-24 |
1973 |
Both |
2 |
|
|
5 |
1 |
|
RIFAMPIN |
TUBERCLE 55:81-9 |
1974 |
Both |
1 |
|
|
5 |
1,7 |
|
RIFAMPIN |
AM REV RESPIR DIS 116:807-20 |
1977 |
Both |
5 |
|
|
5 |
1 |
|
RIFAMPIN |
CHEST 75:441-7 |
1979 |
Both |
|
|
|
5 |
1 |
|
RIFAMPIN |
CHEST 76:782-4 |
1979 |
Both |
|
|
|
5 |
1 |
|
RITUXIMAB |
J CLIN ONCOL 15:3266-3474 |
1997 |
Adult |
3 |
|
|
3 |
NA |
|
RUXOLITNIB PHOSPHATE |
CURR MED CHEM 19: 4399-4413 |
2012 |
|
|
|
|
5 |
3 |
|
RUXOLITNIB PHOSPHATE |
BLOOD 123: 2157-60 |
2014 |
|
|
|
|
5 |
1, 3 |
|
SIROLIMUS |
TRANSPLANTATION 69:2085-90 |
2000 |
Both |
93 |
|
|
5 |
2 |
|
SIROLIMUS |
TRANSPLANT PROC 33:2271-2 |
2001 |
Both |
|
|
|
5 |
1 |
|
SPIRONOLACTONE |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
STREPTOKINASE |
J AM COLL CARDIOL 11:1-11 |
1988 |
Unknown |
|
|
|
5 |
1 |
|
SULFAMETHOXAZOLE |
BLOOD 84:176-83 |
1994 |
Both |
|
|
|
5 |
1 |
|
SULFISOXAZOLE |
ARCH INTERN MED 128:399-404 |
1971 |
Both |
|
|
|
5 |
1 |
|
SULFISOXAZOLE |
BLOOD 84:176-83 |
1994 |
Both |
|
|
|
5 |
1 |
|
TEICOPLANIN |
BR J HAEMATOL 129:279-281 |
2005 |
Unknown |
31 |
31 |
|
3 |
NA |
|
TEICOPLANIN |
J CLIN PHARM THER 37: 296-300 |
2012 |
|
|
|
|
5 |
1 |
|
TEMOZOLOMIDE |
CANCER CHEMOTHER PHARMACOL 52:459-64 |
2003 |
Both |
|
|
|
5 |
3 |
|
TEMOZOLOMIDE |
NEURO ONCOL 9:47-52 |
2007 |
Adult |
|
|
|
5 |
3 |
|
TEMOZOLOMIDE |
NEURO ONCOL 11:825-32 |
2009 |
Adult |
29 |
|
|
5 |
1,3 |
|
TEMSIROLIMUS |
ONCOLOGY 80: 34-41 |
2010 |
|
|
|
|
5 |
|
|
TICLOPIDINE |
CIRC CARDIOVASC INTERV 2:348-51 |
2009 |
Adult |
3 |
|
|
5 |
1 |
|
TIROFIBAN |
CIRCULATION 94 (Suppl):I553 |
1996 |
Unknown |
29 |
16 |
13 |
4 |
NA |
|
TIROFIBAN |
CIRCULATION 96:1445-1453 |
1997 |
Adult |
23 |
13 |
10 |
4 |
NA |
|
TIROFIBAN |
NEJM 228:1488-1497 |
1998 |
Adult |
28 |
19 |
9 |
4 |
NA |
|
TIROFIBAN |
NEJM 338:1488-1497 |
1998 |
Adult |
21 |
15 |
6 |
4 |
NA |
|
TIROFIBAN |
NEJM 338:1498-1505 |
1998 |
Adult |
24 |
18 |
6 |
1 |
NA |
|
TIROFIBAN |
PLATELETS 16:462-8 |
2005 |
Adult |
11 |
|
|
3 |
NA |
|
TIROFIBAN |
EXPERT OPIN DRUG SAF 9:801-19 |
2010 |
Adult |
|
|
|
5 |
1 |
|
TIROFIBAN |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
TNFalpha/INFgamma |
ANN RHEUM DIS 67:1145-52 |
2008 |
Pediatric |
|
|
|
5 |
1 |
|
TNFalpha/INFgamma |
J AM ACAD DERMATOL 60:781-5 |
2009 |
Adult |
4 |
4 |
0 |
2 |
NA |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
CLIN PHARM THER 9:550-560 |
1968 |
Adult |
|
|
|
5 |
2,7 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
ARCH INTERN MED 128:399-404 |
1971 |
Both |
|
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
J INFECT DIS 128:SUPPL:607-12 |
1973 |
Both |
25 |
|
|
3 |
NA |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
LANCET 2:614-6 |
1974 |
Pediatric |
11 |
10 |
1 |
2 |
NA |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
J INFECT DIS 132:630-6 |
1975 |
Both |
1 |
1 |
0 |
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
MED J AUST 2:5-7 |
1976 |
Both |
31 |
|
|
3 |
NA |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
MED J AUST 2:5-7 |
1978 |
Both |
31 |
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
AM J DIS CHILD 135:1097-5 |
1981 |
Pediatric |
|
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
AM J DIS CHILD 135:1100-1103 |
1981 |
Pediatric |
6 |
6 |
0 |
2 |
NA |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
AM J DIS CHILD 136:1029 |
1982 |
Pediatric |
|
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
J PEDIATRIC 100:1002-3 |
1982 |
Pediatric |
|
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
INFECTION 15 (Suppl 5):S248-S252 |
1987 |
NA |
|
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
ARCH INTERN MED 148:2293-5 |
1988 |
Adult |
|
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
J INTERN MED 228:353-360 |
1990 |
Both |
|
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
BR J CLIN PHARMACOL 43:649-651 |
1997 |
Adult |
3 |
|
|
5 |
1 |
|
TRIMETHOPRIM/SULFAMETHOXAZOLE |
EUR J CLIN PHARMACOL 68: 821-32 |
2012 |
|
|
|
|
2 |
|
|
UROKINASE |
J AM COLL CARDIOL
23:891-898 |
1994 |
Adult |
|
|
|
5 |
1 |
|
VALGANCICLOVIR |
DRUGS 61:1145-1150 |
2001 |
Adult |
22 |
|
|
3 |
NA |
|
VALPROIC ACID |
EPILEPSIA 19:113-114 |
1978 |
Pediatric |
6 |
|
|
5 |
3 |
|
VALPROIC ACID |
ANN NEUROL 5:389-390 |
1979 |
Adult |
10 |
|
|
5 |
3 |
|
VALPROIC ACID |
ARCH DIS CHILD 57:681-4 |
1982 |
Both |
15 |
|
|
5 |
3 |
|
VALPROIC ACID |
EPILEPSIA 34:1098-101 |
1993 |
Both |
12 |
0 |
0 |
5 |
3 |
|
VALPROIC ACID |
NEUROLOGY 44:1418-22 |
1994 |
Both |
|
2 |
|
5 |
3 |
|
VALPROIC ACID |
PEDIATR NEUROL 14:303-307 |
1996 |
Pediatric |
41 |
36 |
5 |
5 |
3 |
|
VALPROIC ACID |
AM J PSYCHIATRY 158:128-130 |
2001 |
Adult |
10 |
|
|
5 |
3 |
|
VALPROIC ACID |
HONG KONG MED J 7:15-21 |
2001 |
Pediatric |
17 |
17 |
2 |
5 |
3 |
|
VALPROIC ACID |
PHARMACOTHERAPY 21:1325-1330 |
2001 |
Both |
31 |
|
|
5 |
1,3 |
|
VALPROIC ACID |
J CLIN PSYCHOPHARMACOL 23:451-458 |
2003 |
Adult |
|
|
|
5 |
2,3 |
|
VALPROIC ACID |
EPILEPSIA 47:1136-43 |
2006 |
Pediatric |
|
|
|
5 |
3 |
|
VALPROIC ACID |
EPILEPSIA 48:205-6 |
2007 |
Pediatric |
0 |
|
|
5 |
2,3 |
|
VALPROIC ACID |
EPILEPSIA 49:438-45 |
2007 |
Adult |
71 |
41 |
6 |
5 |
3 |
|
VALPROIC ACID |
BLOOD COAGUL FIBRINOLYSIS 19:375-82 |
2008 |
Pediatric |
2 |
2 |
0 |
5 |
2,3 |
|
VALPROIC ACID |
EPILEPSIA 49:438-45 |
2008 |
Both |
47 |
31 |
4 |
5 |
3 |
|
VALPROIC ACID |
J CLIN PSYCHOPHARMACOL 30:282-5 |
2010 |
Adult |
6 |
|
|
5 |
3 |
|
VANCOMYCIN |
PHARMACOTHERAPY 19:108-113 |
1999 |
Adult |
26 |
9 |
17 |
2 |
NA |
|
VANCOMYCIN |
N ENGL J MED 356:904-10 |
2007 |
Unknown |
|
|
|
5 |
1 |
|
VANCOMYCIN |
NEJM 356: 904-10 |
2007 |
Adult |
29 |
|
|
3 |
NA |
|
VANCOMYCIN |
J CLIN PHARM THER 37: 296-300 |
2012 |
|
|
|
|
5 |
1 |
|
WARFARIN |
CLIN APPL THROMB HEMOST 8:213-215 |
2002 |
Both |
28 |
|
|
5 |
1 |