Pathology Case of the Month

College of American Pathologists (CAP)

Listed by site and type with diagnosis.

Sorted by chronological order  Sorted without diagnosis  Show the codes in a separate window

Type  Code

C-            Congenital malformation

D-           Neurodegenerative disease

F-            Forensic, intoxication, iatrogenic, & medication related

G-           Genetic and/or metabolic

I-             Infection, inflammation, & demyelination

TC-          Neoplastic & non-neoplastic cyst (grossly cystic)

TH-         Neoplasm, hematopoietic, histiocytic, & dendritic

TM-        Metastasis

TN-         Neoplasm & solid tumor-like lesions

TS-          Hyperplasia, dysplasia, in situ neoplasm

U-           Unclassified or mixed

Site	Type	Number	Clinical information	Diagnosis
A2	TN	2019-01-1	A 92 year-old woman with a 6 cm gastric ulcer.	Mucinous adenocarcinoma.
A2	TN	2019-06-1	A 56 year-old man with a 5.2 cm gastric tumor.	Gastrointestinal stromal tumor (GIST).
A4	TN	2018-07-2	A 30 year-old woman with a 20 cm cystic mass causing bowel obstruction.	Lymphangioma.
A6	TH	2019-09-1	A 37 year-old woman with a uterine mass and extensive flattening in the colon accompanied by regional lymph node enlargement.	Non-Hodgkin B-cell lymphoma, low-grade.
A6	TN	2016-05-1	A 58 year-old man with a 2.8 cm pedunculated polyp discovered during surveillance colonoscopy.	Peutz-Jeghers polyp.
A6	TN	2017-06-2	A 21 year-old man with intermittent rectal bleeding.	Familial adenomatous polyposis.
B0	TN	2016-06-3	A 57 year-old with a breast mass. She has a history of invasive ductal carcinoma of the breast 3 years ago.	Epithelioid angiosarcoma.
B0	TN	2016-12-1	A 24 year-old pregnant woman with a 1 cm mass in her breast.	Nodular fasciitis.
B0	TN	2018-03-1	A 21 year-old woman with a 6.5 cm breast mass.	Extranodal Rosai-Dorfman disease.
B0	TN	2019-10-1	An 18 year-old woman with a non-tender breast mass.	Tubular adenoma.
C1	I	2016-03-1	A 57 year-old man with a long history of non-ischemic dilated cardiomyopathy and cardiac transplantation.	Chagas disease (American trypanosomiasis), reactivation after cardiac transplantation.
C1	TN	2017-03-2	A 53 year-old man with a pedunculated mass in his left atrium.	Cardiac (atrial) myxoma.
C1	TN	2019-09-1	A 23 year-old with an 8.5 cm right atrial mass.	Angiosarcoma.
E0	TN	2018-01-1	A 79 year-old woman with a 2.4 cm parotid mass.	Salivary duct carcinoma.
F1	TN	2016-07-1	A 72 year-old woman with a 4.0 cm slowly spreading plaque in the vulva.	Extramammary Paget disease.
F2	TN	2018-02-2	A 35 year-old with a 2.5 cm polypoid mobile mass attached to the left posterior vaginal wall.	Cellular angiofibroma.
F4	TN	2017-08-1	A 56 year-old with abnormal uterine bleeding.	Endometrioid carcinoma.
F4	TN	2018-02-1	A 54 year-old abnormal perimenopausal bleeding and a 10 cm polypoid uterine mass filling her uterine cavity.	Malignant PEComa (perivascular epithelioid cell tumor).
F6	TM	2019-03-2	A 70 year-old woman with bilateral enlarged ovaries and an appendiceal lesion.	Primary appendiceal adenocarcinoma ex goblet cell carcinoid with metastasis to bilateral ovaries
F6	TN	2016-04-1	A 42 year-old woman with a 12 cm ovarian mass.	Mucinous cystadenocarcinoma of ovary, Grade I.
F6	TN	2016-06-1	A 19 year-old woman with a pelvic mass.	Immature teratoma of ovary.
F6	TN	2016-12-2	A 46 year-old woman with progressive hirsutism and a slightly enlarged ovary.	Sertoli-Leydig cell tumor.
F6	TN	2017-02-1	A 53 year-old woman with an 8 cm adnexal mass.	Fibrothecoma.
F6	TN	2017-10-1	A 60 year-old woman with a 10 cm cystic ovarian mass.	Clear cell carcinoma.
F6	TN	2018-06-1	A 24 year-old woman with a 12 cm solid ovarian mass.	Sclerosing stromal tumor.
F6	TN	2020-02-1	A 29 year-old woman with a 12 cm solid left ovarian mass.	Dysgerminoma.
F6	TN	2020-03-2	A 58 year-old woman with a 14 cm ovarian mass.	Adult granulosa cell tumor.
F6	TN(P)	2017-12-1	A 9 year-old girl with a right adnexal mass.	Juvenile granulosa cell tumor.
F7	I	2017-02-2	A 34 year-old woman presents at 27 weeks gestation with decreased fetal movement for three days, fever, chills, and body aches.	Fusobacterium nucleatum infection.
F7	I	2018-12-1	A 22 year-old 37 weeks pregnant woman with fetal distress.	Chronic villitis of unknown etiology.
F7	TN	2019-07-1	A 19 year-old woman with vaginal bleeding during the 14th week of pregnancy.	Gestational trophoblastic disease, complete molar type.
F7	U	2019-06-2	A 24 year-old woman with profuse vaginal bleeding.	Placenta increta.
G1	TM	2020-04-3	A 65 year-old man with a testicular mass.	Metastatic prostatic adenocarcinoma.
G1	TN	2016-11-1	A 20 year-old man with an enlarging testicular mass.	Yolk sac tumor.
G1	TN	2017-07-1	A 42 year-old man with a 5 cm testicular mass.	Seminoma.
G1	TN	2019-01-2	A 35 year-old man with a 7 cm testicular mass.	Mixed germ cell tumor.
G3	TN	2019-05-2	A 44 year-old man with a 10 cm exophytic, fungating penile mass.	Squamous cell carcinoma, poorly differentiated.
H0	I	2017-11-2	A 28 year-old man with generalized adenopathy and weight loss.	Granulomatous lymphadenitis/sarcoidosis.
H0	TH	2017-04-2	A 48 year-old man with a growing right neck mass.	Hodgkin-lymphoma, classical.
H0	TH	2017-09-2	An 80 year-old woman with splenomegaly.	Splenic marginal zone lymphoma.
H0	TH	2018-09-1	A 65 year-old with a large abdominal mass involving the transverse colon and abdominal lymphadenopathy.	Diffuse large B-cell lymphoma.
H0	TM	2019-11-2	A 62 year-old man with an enlarged left internal iliac lymph node.	Metastatic prostatic adenocarcinoma.
H0	TN	2016-04-2	An 80 year-old man with a rapidly enlarging firm mobile inguinal mass.	Merkel cell carcinoma.
H0	TN	2016-10-2	A 52 year-old with an 8 cm mesenteric mass and history of rectal adenocarcinoma.	Nodular lymphocyte-predominant Hodgkin lymphoma.
H0	TN	2017-09-1	A 66 year-old man with splenomegaly.	Littoral cell angioma.
H0	TN	2019-10-2	A 56 year-old woman with a mass over her left lower thorax.	Littoral cell angioma.
H0	U	2016-02-1	A 63 year-old man with progressive pancytopenia and a ruptured spleen.	Splenic extramedullary hematopoiesis secondary to primary myelofibrosis.
H0	U	2019-05-3	A 67 year-old woman with splenomegaly.	Sclerosing angiomatoid nodular transformation.
H0	U(P)	2018-12-2	A 38 weeks gestation boy with up-slanting eyes, webbed toes, and a mumur consistent with a ventricular septal defect.	Circulating blasts in neonates.
J0	TN	2016-07-2	A 60 year-old man with a 2.5 cm lesion in his left upper lobe of lung.	Adenocarcinoma, predominantly acinar type
J0	TN	2018-09-2	A 77 year-old with a 5 cm lung nodule	Invasive mucinous adenocarcinoma/colloid carcinoma.
J0	TN	2020-03-1	A 66 year-old woman with a 10 cm mass at the periphery of her right upper lobe of lung.	Pulmonary adenocarcinoma, predominantly papillary type.
K1	I	2017-05-1	A 50 year-old woman with sudden onset flank pain and low-grade fever, an irregular kidney with dilated pelvis.	Chronic pyelonephritis with granulomas.
K1	TN	2016-03-2	A 52 year-old woman with gross hematuria and a left flank mass.	Chromophobe renal cell carcinoma.
K1	TN	2016-09-2	A 59 year-old man with a 10 cm renal mass.	Papillary renal cell carcinoma, type 1.
K1	TN	2017-11-1	A 67 year-old man with a 10.5 cm renal mass.	Sarcomatoid renal cell carcinoma.
K1	TN	2019-02-1	A 37 year-old woman with a 10 cm renal mass.	Angiomyolipoma.
K1	TN	2019-03-1	A 67 year-old man with a 13.8 cm renal mass.	Renal cell carcinoma with rhabdoid differentiation.
K1	TN(P)	2016-08-1	A 3 month-old infant with a palpable abdominal mass.	Congenital mesoblastic nephroma.
K1	TN(P)	2017-10-2	A 9 month-old boy with a 6.5 cm renal mass.	Nephroblastoma (Wilms tumor).
K1	TN(P)	2020-04-1	A 2 year-old boy with a right upper quadrant mass.	Mesoblastic nephroma/congenital mesoblastic nephroma of the kidney.
K2	TN	2020-04-2	A 44 year-old woman with a large mass arising in the posterior wall of the bladder.	Leiomyosarcoma of the bladder.
L1	I	2018-03-2	A 19 year-old man with a history of polycythemia vera and epigastric pain for several days. .	Budd-Chiari syndrome (primary).
L1	I	2020-02-2	A 39 year-old man with cholecdocholithiasis, prominent appearing extrahepatic bile ducts, and a vague mass near the hilum of the liver as demonstrated by ultrasound.	Primary sclerosing cholangitis of the liver.
L1	TC	2018-10-1	A 41 year-old woman with a 12 cm cyst in her left lobe of liver.	Hepatobiliary cystadenoma.
L1	TM	2018-04-2	A 74 year-old man with numerous masses in the distal small intestine and liver.	Metastatic neuroendocrine tumor.
L1	TM	2020-05-1	A 36 year-old woman with a left hepatic mass.	Metastatic pheochromocytoma.
L1	TN	2017-06-1	A 42 year-old woman with multiple nodules involving the liver.	Hepatic epithelioid hemangiothelioma.
L1	TN	2018-05-2	A 39 year-old woman with a liver mass. (The clinical information and choices for diagnosis in this case is a mismatch. The image and the discussion are correct.)	Hepatic nuclear factor 1 alpha (HNF1A)-inactivated hepatocellular adenoma.
L1	TN	2018-08-1	A 24 year-old woman with a 5.3 m well-circumscribed hepatic nodule.	Focal nodular hyperplasia.
L1	TN(P)	2016-02-2	A 9 year-old boy with a 12.5 cm liver mass.	Undifferentiated embryonal sarcoma of liver.
L1	TN(P)	2016-11-2	A 23 year-old delivered a female neonate at 32 weeks’ gestation with low Apgar score and thrombocytopenia.	Chorangioma.
L1	TN(P)	2019-04-1	A 4 year-old boy with a history of partial hepatectomy and now with multiple hepatic nodules.	Heatoblastoma.
L1	U	2018-06-2	A 66 year-old man with combined heart and liver transplantation.	Amyloidosis.
L3	TN	2019-10-3	A 26 year-old woman with an 8 cm mass in her pancreas.	Solid-pseudopapillary neoplasm.
M0	TB	2017-07-2	A 48 year-old woman with a 12.5 cm intrathoracic, mediastina, well-circumscribed mass.	Cellular schwannoma.
M0	TH(P)	2019-12-2	A 14 year-old boy with a large anterior mediastinal mass.	T- lymphoblastic leukemia/lymphoma.
M0	TN	2016-10-1	A 33 year-old woman with myasthenia gravis and a 10 cm anterior mediastinal mass.	Thymoma, WHO type AB.
M0	TN	2019-04-2	A 41 year-old with a mediastinal mass.	Thymoma.
M0	TN(P)	2018-04-1	A 3 year-old girl with an incidental posterior mediastinal mass.	Ganglioneuroma.
M0	TS	2018-09-3	A 71 year-old man with a thymic mass.	Thymic follicular hyperplasia.
N0	TN	2016-01-1	A 57 year-old man with a sacral osteolytic mass compressing the surrounding nerves.	Chordoma.
N0	TN	2018-10-2	A 68 year-old woman with a 4 cm parasagittal mass in her parietal lobe.	Meningioma.
P0	TN	2017-04-1	A 62 year-old woman with pleural effusion and multiple pleural tumor nodules on the right side.	Biphasic mesothelioma.
P0	TN	2018-05-1	A 57 year-old woman with a large omental cake.	Serous carcinoma.
R0	TN	2016-09-1	A 49 year-old woman with a 15 cm adrenal mass.	Adrenal cortical carcinoma.
S0	TN	2016-06-2	A 60 year-old man with abdominal pain and a 7 cm mesenteric mass.	Solitary fibrous tumor.
S0	TN	2016-08-2	A 32 year-old with a 6.3 cm deep soft tissue mass in his thigh.	Low-grade fibromyxoid sarcoma.
S0	TN	2017-08-2	A 48 year-old woman with a deep 7 cm mass in vulvar region.	Aggressive angiomyxoma.
S0	TN	2018-01-3	A 4 year-old with an 8 cm paravertebral mass focally extending into the spinal canal.	Ganglioneuroblastoma.
S0	TN	2018-07-1	A 47 year-old man with a superficial posterior neck mass.	Spindle cell/pleomorphic lipoma.
S0	TN	2019-02-2	A 72 year-old woman with a 7 cm deep mass in her upper extremity.	Pleomorphic liposarcoma.
S0	TN	2019-05-1	A 47 year-old woman with a 5.2 cm thigh mass.	Myxoid liposarcoma.
S0	TN	2019-11-1	A 45 year-old with a 4.5 cm mass in her left flank.	Granular cell tumor.
S0	TN	2020-01-1	A 71 year-old with a 32 cm retroperitoneal mass.	Leiomyosarcoma.
S0	TN(P)	2017-01-2	A 26 month-old boy with a 4.5 cm thigh mass without cutaneous involvement.	Extrarenal malignant rhabdoid tumor.
S0	TN(P)	2018-11-1	A 13 year-old boy with a 5 cm soft tissue mass the posterior aspect of his knee.	Myositis ossificans circumscripta.
T0	I	2017-05-2	A 48 year-old woman with hypothyroidism and a firm to hard thyroid.	Hashimoto thyroiditis, fibrous atrophy variant.
T0	TN	2019-09-2	A 70 year-old woman with a 7 cm supraclavicular neck mass.	Anaplastic thyroid carcinoma with heterologous differentiation (leiomyosarcoma).
T0	TS	2017-01-1	A 40 year-old woman, with a thyroid nodules.	Nodular thyroid hyperplasia (mutinodular goiter).
W0	TN	2019-12-1	A 57 year-old man with an 8 cm mass in his sacral area.	Chordoma.
W0	TN TN	2016-01-2	A 65 year-old man with a painful left intramedullary pelvic mass.	Chondrosarcoma grade 2 of 3.
Z0	I	2018-01-2	A 62 year-old woman with an 8 cm indurated rash on the right calf.	A Classic Case of Pasteurella multocida.
Z0	I	2018-11-2	A 45 year-old with an infected wound.	Fungal infection due to hyalohyphomycotic organism
Z0	TN	2017-03-1	A 72 year-old man with a large exophytic and fungating mass involving the amputation stump.	Invasive squamous cell carcinoma, well-differentiated.