Anatomic Pathology Case of the Month
Univeristy of Pittsburgh Medical Center (UPMC)
Listed by site and type with diagnosis.
Sorted by chronological order Sorted without diagnosis Show the codes in a separate window
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A0: Alimentary canal |
F0: Female genital system
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L0: Hepatobiliary tract &
pancreas |
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A1:
Esophagus |
F1:
Female external genitalia |
L1:
Liver |
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A2:
Stomach |
F2:
Vagina |
L2:
Gallbladder & extrahepatic biliary
track |
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A3:
Duodenum |
F3:
Uterine cervix |
L3:
Pancreas |
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A4:
Small intestine
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F4:
Uterine corpus & soft tissue |
M0: Mediastinum & thymus |
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A5:
Appendix |
F5:
Fallopian tube |
N0: Central nervous system
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A6:
Colon |
F6:
Ovary |
N1:
Nerve & muscle biopsy |
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A7:
Rectum and anus |
F7: Placenta and trophoblasts |
O0: Eye & orbit |
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B0: Breast & skin of
breast |
G0: Male genital system |
P0: Pleura, peritoneum,
mesentery, & omentum |
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C0: Cardiovascular system
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G1:
Testis & related structures |
Q0: Head & neck, miscellaneous |
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C1:
Heart |
G2:
Prostate & seminal vesicles |
R0: Adrenal & paraganglia
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C2:
Major blood vessels |
G3:
Penis & related structures |
S0: Soft tissue &
peripheral nerve (surgical) |
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D0: Oral cavity, mandible, &
maxilla |
H0: Bone marrow, lymph nodes &
spleen |
T0: Thyroid & parathyroid
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|
D1: Mucosa, soft tissue, & tongue |
I0: Larynx & upper
respiratory tract |
T1: Thyroid |
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D2:
Mandible & maxilla |
J0: Lung & lower
respiratory tract |
T2: Parathyroid |
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E0: Major salivary glands |
K0: Urinary system &
adrenal |
U0: Pituitary gland & sellar
area |
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K1:
Kidney, surgical |
V0: Small blood vessels &
lymphatics |
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K2:
Ureter, bladder, urachus, & urethra |
W0: Bone & joint |
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K3:
Kidney, medical |
X0: Miscellaneous &
unclassified |
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Z0: Skin |
|
Type |
|
C-
Congenital malformation |
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D-
Neurodegenerative disease |
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F-
Forensic, intoxication, iatrogenic, & medication related |
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G-
Genetic and/or metabolic |
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I-
Infection, inflammation, & demyelination |
|
TC-
Neoplastic & non-neoplastic cyst (grossly cystic) |
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TH-
Neoplasm, hematopoietic, histiocytic, & dendritic |
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TM-
Metastasis |
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TN-
Neoplasm & solid tumor-like lesions |
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TS-
Hyperplasia, dysplasia, in
situ neoplasm |
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U-
Unclassified or mixed |
| (P)- Pediatric & perinatal |
| (C)- Cytology |
|
Site |
Type |
Case Number |
Clinical information |
Diagnosis |
|
A0 |
U |
A 6 year-old female transplant
patient presents with fever and rectal bleeding. |
Malakoplakia of allograft gastrointestinal tract including
stomach, ileum, and colon and native colon. |
|
|
A0 |
U |
A woman in her 40s with
endometriosis and bland glandular inclusions. |
Endometriosis of ileocecal junction, focal endometriosis in
two of seventeen lymph nodes, bland glandular inclusions in two of
seventeen lymph nodes. |
|
|
A0 |
C(P) |
A child with hirschsprung disease. |
Total intestinal aganglionosis with a segment of
dysganglionosis in the submucosa of proximal jejunum |
|
|
A1 |
TN |
A 46 year-old female with a nodule
at the mid esophagus. |
Esophageal granular cell tumor associated with
pseudoepitheliomatous hyperplasia. |
|
|
A1 |
TS |
A 46 year-old female with a nodule
at the mid esophagus. |
Esophageal granular cell tumor associated with
pseudoepitheliomatous hyperplasia. |
|
|
A2 |
I |
Gastric biopsy from man in his
40's - can AI make the diagnosis? |
Helicobacter pylori gastritis |
|
|
A2 |
I |
An 18-year-old woman with
abdominal pain. |
Intense gastritis with reactive lymphoid infiltrate
compatible with Epstein-Barr virus related gastritis. |
|
|
A2 |
I |
A 64-year-old woman with a long
history of irritable bowel syndrome. |
Poorly differentiated gastric adenocarcinoma with metastatic
disease involving the colon arising in a background of chronic active
gastritis with incomplete intestinal metaplasia with heavy colonization
by Helicobacter pylori. |
|
|
A2 |
TN |
A 64-year-old woman with a long
history of irritable bowel syndrome. |
Poorly differentiated gastric adenocarcinoma with metastatic
disease involving the colon arising in a background of chronic active
gastritis with incomplete intestinal metaplasia with heavy colonization
by Helicobacter pylori. |
|
|
A2 |
TS |
A 30 year-old female with multiple
gastric polyps. |
Fundic gland polyps with focal low-grade dysplasia. |
|
|
A2 |
U |
A 70 year-old male with a gastric
mass. |
Menetrier's disease. |
|
|
A3 |
TM |
A 71 year-old male with right
flank pain. |
Metastatic seminoma in the duodenum. |
|
|
A3 |
U |
A 23 year-old male with portal
hypertension in the stomach and an erythematous proximal jejunum. |
Pseudomelanosis duodeni. |
|
|
A4 |
TN |
A 69-year-old male with a history
of colonic adenocarcinoma. |
Invasive well-differentiated mucin producing adenocarcinoma
arising in a small bowel villous adenoma. |
|
|
A5 |
TN |
A 68 year-old female with acute
appendicitis. |
Goblet cell carcinoid. |
|
|
A6 |
I |
A male in his 20s with HIV,
diarrhea and abdominal pain. |
Cytomegalovirus (CMV) colitis, intestinal spirochetosis.
infection (CMV colitis) |
|
|
A6 |
I |
A 52 year-old woman with
gastrointestinal bleeding and a history of rheumatoid arthritis. |
Necrotizing leukocytoclastic small vessel vasculitis of the
colon, of probable autoimmune etiology. |
|
|
A6 |
TN |
A 71 year-old male with a right
colonic mass. |
Mixed adenoneuroendocrine carcinoma- signet ring type. |
|
|
A6 |
TN |
An 83 year-old female with a lower
gastrointestinal bleed and multiple lesions. |
Mixed neuroendocrine carcinoma of the cecum. |
|
|
A6 |
TN |
A 52-year-old male with a 3 week
history of abdominal pain. |
Leiomyosarcoma, myxoid variant. |
|
|
A6 |
TN |
A 53-year-old man with abdominal
distention. |
Pseudomyxoma peritonei, peritoneal mucinous carcinomatosis
of presumed appendiceal origin. |
|
|
A7 |
I |
A 35-year-old male with rectal
bleeding. |
Schistosomiasis. |
|
|
A7 |
U |
A 41 year-old male with rectal
bleeding. |
Brown bowel syndrome |
|
|
A7 |
U |
A 58-year-old female with a
colonic mass. |
Polypoid endometriosis with transmural involvement of
rectosigmoid colon. Endometriosis shows foci of simple hyperplasia and
mucinous metaplasia. |
|
|
B0 |
TC |
A peculiar mucinous tumor of the
breast. |
Mucinous cystadenocarcinoma of the breast. |
|
|
B0 |
TH |
A 65-year-old woman with malignant
lymphoma. |
Malignant lymphoma, small B-cell type with plasmacytic
differentiation and crystal-storing histiocytosis. |
|
|
B0 |
TN |
A woman in her 50's with a breast
mass. |
Malignant adenomyoepithelioma |
|
|
B0 |
TN |
A 74-year-old female with a breast
mass a breast mass. |
Metaplastic carcinoma of the breast, spindle cell type. |
|
|
B0 |
TN |
A 71 year-old woman with a mass in
left breast. |
Carcinosarcoma (high-grade malignant phylloides tumor with
high-grade mammary carcinoma). |
|
|
B0 |
TN |
A 59-year-old woman with a nodule
in the right breast. |
Myofibroblastoma, epithelioid type. |
|
|
B0 |
TN |
A 54-year-old female with a left
breast mass. |
Adenoid cystic carcinoma, grade II of III. |
|
|
B0 |
TN |
A 42 year-old woman with right
breast mass. |
Metaplastic carcinoma of the breast, matrix producing type,
(poor nuclear grade). |
|
|
B0 |
TS |
A 64-year-old female with left
nipple discharge and an inverted nipple. |
Paget's disease of the breast. |
|
|
B0 |
U |
A 43 year-old woman with a
palpable breast mass. |
Sinus histiocytosis with massive lymphadenopathy
(Rosai-Dorfman disease). |
|
|
C1 |
G |
A 4 year-old boy with
cardiomyopathy |
Desmin cardiomyopathy. |
|
|
C1 |
I |
A 72 year-old white female with
respiratory distress. |
Idiopathic giant cell myocarditis. |
|
|
C1 |
U |
A man at 70s had episodes of
syncope. |
Sarcoidosis involving the myocardial conduction system. |
|
|
C1 |
U |
A 73 year-old male had a heart
transplant. |
Heterotopic breast epithelial inclusion of the heart. |
|
|
C1 |
U |
A 37-year-old female with sudden
onset of cardiac arrhythmias following a flu-like illness. |
Arrhythmogenic right ventricular cardiomyopathy. |
|
|
C1 |
U(P) |
An 11 year-old female who
collapsed during out-patient clinic visit. |
Left ventricular non-compaction. |
|
|
C2 |
TN |
A 67 year-old man with progressive
shortness of breath. |
Rhabdomyosarcoma of pulmonary artery trunk. |
|
|
D1 |
C |
A 45 year-old man with a midline
tongue lesion. |
Foregut duplication cyst of the tongue. |
|
|
D1 |
TH |
A 66-year-old male with a history
of precursor B-cell acute lymphoblastic leukemia now presents with an
upper lip soft tissue mass. |
Histiocytic neoplasm, post-acute lymphoblastic leukemia. |
|
|
D1 |
TN(P) |
A term female neonate with two
oral cavity masses. |
Congenital epulis (congenital granular cell tumor) |
|
|
D2 |
TN(P) |
A preadolescent male presented to
a dental clinic with an asymptomatic swelling in the oral cavity. |
Primordial odontogenic tumor with hard tissue formation. |
|
|
E0 |
TN |
A woman in her 60s with a parotid
mass. |
Basal cell adenocarcinoma
ex pleomorphic adenoma, tubular, trabecular and cribriform
patterns, with oncocytic differentiation. |
|
|
E0 |
TN |
A 61 year-old female with a
right-sided submandibular gland mass. |
Mucoepidermoid carcinoma, high-grade. |
|
|
E0 |
TN |
A 53 year-old woman with a parotid
gland mass. |
Sebaceous lymphadenoma. |
|
|
E0 |
TN(P) |
A year-old boy with a parotid
lump. |
Mammary analogue secretory carcinoma of salivary gland |
|
|
F0 |
TN |
A woman in her 50s with severe
pain in right lower quadrant and vomiting. |
Synchronous endometrioid adenocarcinomas of the endometrium
and right ovary associated with extensive endometriosis. |
|
|
F0 |
U |
A 58-year-old female with a
colonic mass. |
Polypoid endometriosis with transmural involvement of
rectosigmoid colon. Endometriosis shows foci of simple hyperplasia and
mucinous metaplasia. |
|
|
F0 |
U |
A woman in her 50s with severe
pain in right lower quadrant and vomiting. |
Synchronous endometrioid adenocarcinomas of the endometrium
and right ovary associated with extensive endometriosis. |
|
|
F0 |
U(P) |
A two-year-old male with left
undescended
testis. |
Persistent Müllerian duct syndrome. |
|
|
F1 |
TN |
A female in her 30s with an
enlarging left labial mass |
Fibroadenoma of the vulva. |
|
|
F1 |
TN |
A 35 year-old woman with a vulvar
mass |
Atypical myxoid tumor: favor atypical myxoid leiomyoma of
the vulva. |
|
|
F2 |
TN |
Post-menopausal female with
bleeding and vaginal bulge. |
Leiomyo-adenomatoid tumor |
|
|
F3 |
TN |
A 33 year-old woman with post
coital bleeding and vaginal discharge. |
Poorly differentiated glassy cell carcinoma (adenosquamous)
of the uterine cervix. |
|
|
F4 |
TN |
A 57-year-old woman with
postmenopausal bleeding. |
Malignant Müllerian mixed tumor, heterologous type. |
|
|
F4 |
TN(P) |
An adolescent female with
abdominal fullness and distension. |
Based on the morphologic appearance and immunophenotype,
this tumor was diagnosed as a leiomyoma. |
|
|
F4 |
U(C) |
A 57 year-old postmenopausal woman
with spotting and underwent a routine papanicolaou test-pap smear. |
Endometrial cells present in a postmenopausal woman. |
|
|
F6 |
I |
A 63-year-old woman with brain
metastases and diverticulitis. |
Bilateral cytomegalovirus (CMV) associated acute oophoritis
with cortical necrosis. |
|
|
F6 |
TC |
A 65 year-old female with a large
solid-cystic adnexal mass. |
Moderate to poorly differentiated Sertoli-Leydig cell tumor. |
|
|
F6 |
TN |
A post-menopausal female with an
ovarian mass. |
Clear cell carcinoma of the ovary |
|
|
F6 |
TN |
A post-menopausal female with an
ovarian mass. |
Intermediately differentiated Sertoli-Leydig cell tumor with
mucinous adenocarcinoma as heterologous element. |
|
|
F6 |
TN |
A 24-year-old female with gradual
onset of abdomen pain. |
Synovial sarcoma. |
|
|
F6 |
TN |
A 47 year-old woman with a thigh
mass. |
Follicular thyroid carcinoma arising in
struma ovarii with metastasis
to the thigh. |
|
|
F6 |
TN |
A woman in her 40s with an ovarian
mass. |
Micropapillary carcinoma (non-invasive type) of the ovary
associated with a mature cystic teratoma (dermoid cyst). |
|
|
F6 |
TN |
A female in her 70s with pelvic
masses |
Moderately to poorly differentiated non-small cell
neuroendocrine carcinoma. |
|
|
F6 |
TN(P) |
Adolescents with ovarian masses. |
Mixed sex cord/germ cell tumor, gonadoblastoma and germinoma
with granulomatous features, immature teratoma with yolk sac tumor. |
|
|
F6 |
TN |
Ovarian mass in a woman at her 50s
with endometriosis. |
Clear cell carcinoma of right ovary with endometrioid and
papillary features, sigmoid colon and omentum positive for metastatic
carcinoma, right fallopian tube, sigmoid colon, left ovary, and appendix
with endometriosis. |
|
|
F6 |
TN(P) |
A 15-year-old girl with an ovarian
mass. |
Sex cord stromal tumor with combined poorly differentiated
juvenile granulosa and Sertoli Leydig differentiation, recurrent sex
cord stromal tumor with metastatic serosal implantation of sigmoid colon
epiploica and omentum. |
|
|
F6 |
TN(P) |
A teenage female with an ovarian
mass. |
Small cell carcinoma of the ovary, hypercalcemic type |
|
|
F6 |
TS |
A woman in her 60s with an
incidental finding in the left ovary. |
Hilus (or Leydig) cell hyperplasia. |
|
|
F7 |
U |
A 36-week dichorionic-diamniotic
twin placenta. |
Multi-cystic placental lesions. |
|
|
F7 |
U |
A 36 year-old female with early
intrauterine loss of twin B. |
Placenta "A": reactive amnion with moderate meconium
containing macrophages; Placenta "B": complete hyalinization and loss of
fetal vessels. |
|
|
F7 |
U(P) |
A still born fetus (32 weeks
gestation) from a mother with multiple medical problems. |
Intrauterine fetal demise due to multifocal chorangiomatosis
of the placenta. |
|
|
G0 |
TN |
A woman presented with severe back
pain and lytic lesions in lumbar spine and a pelvic mass. |
Primitive neuroectodermal tumors/Ewing sarcoma. |
|
|
G0 |
U |
A woman in her 40s with
endometriosis and bland glandular inclusions. |
Endometriosis of ileocecal junction, focal endometriosis in
two of seventeen lymph nodes, bland glandular inclusions in two of
seventeen lymph nodes. |
|
|
G0 |
U(P) |
A two-year-old male with left
undescended
testis. |
Persistent Müllerian duct syndrome. |
|
|
G1 |
G |
Alström syndrome in an adolescent
male and a review of the literature. |
Mixed germ cell tumor (embryonal carcinoma; yolk sac tumor,
post-pubertal type; teratoma, post-pubertal type) with invasion of the
rete testis, lymphovascular invasion and germ cell neoplasia in-situ. |
|
|
G1 |
G(P) |
A 16 year-old male with a right
testicular mass. |
Large cell calcifying Sertoli cell tumors, multifocal,
Leydig cell hyperplasia (Carney complex). |
|
|
G1 |
TC(P) |
A 15 year-old male with a left
testicular mass. |
Sertoliform cystadenoma of the rete testis. |
|
|
G1 |
TN |
Alström syndrome in an adolescent
male and a review of the literature. |
Mixed germ cell tumor (embryonal carcinoma; yolk sac tumor,
post-pubertal type; teratoma, post-pubertal type) with invasion of the
rete testis, lymphovascular invasion and germ cell neoplasia in-situ. |
|
|
G1 |
TN |
An 80-year-old man with a right
paratesticular mass. |
Paratesticular angiosarcoma following radiation therapy for
prostatic adenocarcinoma. |
|
|
G1 |
TN |
An 80-year-old man with a right
paratesticular mass. |
Paratesticular angiosarcoma following radiation therapy for
prostatic adenocarcinoma. |
|
|
G1 |
TN |
A 33 year-old male with testicular
discomfort. |
Papillary cystadenoma of the epididymis. |
|
|
G1 |
TN |
A 71 year-old man with a left
testicular mass. |
Leydig cell tumor. |
|
|
G1 |
TN(P) |
An infant with pain over the left
scrotum. |
Juvenile granulosa cell tumor. |
|
|
G1 |
TN(P) |
A 7 month-old baby with an
incidental testicular tumor and congenital nephrotic syndrome. |
Denys-Drash syndrome. Dysgenetic testis with juvenile
granulosa cell tumor. Blastematous Wilms tumor in right kidney, and
nephroblastematosis. |
|
|
G1 |
TN(P) |
A 16 year-old male with a right
testicular mass. |
Large cell calcifying Sertoli cell tumors, multifocal,
Leydig cell hyperplasia (Carney complex). |
|
|
G1 |
U(P) |
A 4 week-old boy with an abdominal
mass. |
Intratesticular fetus
in fetu. |
|
|
G2 |
TN |
A middle aged male with a seminal
vesicle mass. |
High-grade epithelial stromal tumor of the left seminal
vesicle. |
|
|
G2 |
TN |
A 72 year-old man with elevated
PSA. |
Prostatic adenocarcinoma with pleomorphic and ductal
features, Gleason score 4+5. |
|
|
G2 |
TN |
A 68 year-old white male with
bladder outlet obstruction. |
Poorly differentiated prostatic adenocarcinoma, Gleason
4+5=9 with high-grade prostatic intraepithelial neoplasia and chronic
prostatitis. |
|
|
G2 |
TN |
An 84 year-old man with bladder
outlet obstruction. |
Prostatic adenocarcinoma, large duct type (also known as
endometrioid adenocarcinoma or ductal adenocarcinoma). |
|
|
H0 |
TH |
A man in his 50s with acute onset
aphasia and right sided weakness. |
Intravascular lymphoma, large B-cell type. |
|
|
H0 |
TH |
A 61-year-old female with a mass
in the right supraclavicular area. |
Non-Hodgkin lymphoma, peripheral T-cell type, with features
of ALK-1 negative anaplastic large cell lymphoma. |
|
|
H0 |
TH |
A 48 year-old female with
persistent fever, fatigue, loss of appetite and weight loss after
surgery. |
Intravascular lymphomatosis (intravascular lymphoma). |
|
|
H0 |
TH |
A 51 year-old female with morbid
obesity and abdominal pain, severe constipation and thirst. |
B-cell lymphoid neoplasm with high-grade features (abdominal
lymphomatosis) |
|
|
H0 |
TH |
A 76 year-old woman with a left
thigh mass |
Primary cutaneous follicle center lymphoma. |
|
|
H0 |
TH |
A 66-year-old male with a history
of precursor B-cell acute lymphoblastic leukemia now presents with an
upper lip soft tissue mass. |
Histiocytic neoplasm, post-acute lymphoblastic leukemia. |
|
|
H0 |
TH |
A 41 year man with sharp pain in
the right side of his rib cage. |
Langerhans cell histiocytosis. |
|
|
H0 |
TH |
A 65-year-old woman with malignant
lymphoma. |
Malignant lymphoma, small B-cell type with plasmacytic
differentiation and crystal-storing histiocytosis. |
|
|
H0 |
TH |
A male in his 60s with plasma cell
neoplasm, favor solitary plasmacytoma of bone. |
Plasma cell neoplasm, favor solitary plasmacytoma of bone. |
|
|
H0 |
TH |
A male in his 30s with a
mediastinal mass. |
Mediastinal B-cell lymphoma. |
|
|
H0 |
TH |
A 51 year-old woman with a nasal
mass. |
Malignant lymphoma, extranodal NK/T-cell lymphoma, nasal
type, most likely of natural killer cell origin. |
|
|
H0 |
TH |
A 71 year-old man with acute renal
failure. |
Waldenstrom's macroglobulinemia with advanced amyloidosis,
atypical, monoclonal lymphoplasmacytic interstitial infiltrate with
admixed reactive T-lymphocytes; consistent with renal interstitial
involvement by lymphoplasmacytic lymphoma. |
|
|
H0 |
TH |
A 24 year-old man with end-stage
restrictive lung disease and liver disease. |
Langerhans Cell Histocytosis. |
|
|
H0 |
TH |
A 65 year-old female with right
neck mass. |
Follicular dendritic cell tumor involving thyroid and right
cervical lymph nodes. |
|
|
H0 |
TH(C) |
A male in his 80s with left sided
neck mass-FNA. |
Alk-1 positive anaplastic large cell lymphoma. |
|
|
H0 |
TH(P) |
A 6 year-old girl with
a large left neck mass. |
Post-transplant lymphoproliferative disorder (PTLD) of the
Burkitt lymphoma type. |
|
|
H0 |
TH(P) |
A 7 year-old boy with multiple
skin lesions. |
CD30 positive lymphoproliferative disorder of the skin. |
|
|
H0 |
TN |
A 69-year-old woman with a groin
mass. |
Merkel cell carcinoma. |
|
|
H0 |
TN |
A 44 year-old female with a
splenic mass. |
Sclerosing angiomatoid nodular transformation of spleen |
|
|
H0 |
U |
A woman in her 70s with a bladder
mass. |
Clear cell adenocarcinoma associated with nephrogenic
adenoma, adenocarcinoma in situ, intestinal metaplasia and lymph node
involvement by endosalpingiosis. |
|
|
H0 |
U |
A 43 year-old woman with a
palpable breast mass. |
Sinus histiocytosis with massive lymphadenopathy
(Rosai-Dorfman disease). |
|
|
H0 |
U |
A 17 year-old female with left
upper neck mass. |
Angiofollicular hyperplasia (Castleman's disease),
hyaline-vascular type. |
|
|
H0 |
U |
A 74-year-old man with a right
thigh mass. |
Extranodal Rosai-Dorfman disease. |
|
|
I0 |
TH |
A 51 year-old woman with a nasal
mass. |
Malignant lymphoma, extranodal NK/T-cell lymphoma, nasal
type, most likely of natural killer cell origin. |
|
|
I0 |
TN |
A nasopharyngeal mass in an
87-year-old woman. |
Malignant melanoma. |
|
|
J0 |
C(P) |
A neonate with spontaneous
pneumothorax and progressive respiratory failure. |
Alveolar capillary dysplasia with misalignment of pulmonary
veins. |
|
|
J0 |
F |
A 55 year-old male with recurrent
spontaneous pneumothoraces. |
Talc granulomatosis due to intravenous drug abuse. |
|
|
J0 |
I |
A 25 year-old white male with a
history of schizoaffective disorder and difficult breathing. |
Staphylococcus aureus pneumonia complicating influenza. |
|
|
J0 |
I |
A 39 year-old man with lung
abscess. |
Severe right lung necrotizing pneumonia with mucormycosis. |
|
|
J0 |
I |
A 59 year-old male with lung mass. |
Pneumonia associated with
Cryptococcus neoformans. |
|
|
J0 |
TC(P) |
A newborn with large, thin-walled
cysts in the left hemithorax. |
Cystic pleuropulmonary blastoma. |
|
|
J0 |
TH |
A 46 year-old man with a right
lower lobe pulmonary mass. |
Primary adenocarcinoma of lung with clear cell features
associated with pulmonary Langerhans cell histiocytosis. |
|
|
J0 |
TN |
A middle aged female with left
lower lobe lung mass. |
Sclerosing pneumocytoma |
|
|
J0 |
TN |
A 65-year-old female with an
incidental lung mass. |
Sclerosing hemangioma |
|
|
J0 |
TN |
A 66-year-old female with a lung
mass. |
Pulmonary cavernous hemangioma. |
|
|
J0 |
TN |
A 77 year-old man with worsening
dyspnea. |
Diffusely infiltrating, moderately differentiated left lung
primary adenocarcinoma, diffuse interstitial pulmonary fibrosis/usual
interstitial pneumonia. |
|
|
J0 |
TN |
A 46 year-old man with a right
lower lobe pulmonary mass. |
Primary adenocarcinoma of lung with clear cell features
associated with pulmonary Langerhans cell histiocytosis. |
|
|
J0 |
TN |
A 62 year-old woman with back
pain. |
Invasive poorly differentiated adenocarcinoma of lung with
vertebral metastasis. |
|
|
J0 |
TN |
A 34 year-old male with a large
right lung mass. |
Invasive pulmonary thymoma, mixed lymphoepithelial type,
with extensive pleural spread. |
|
|
J0 |
TN |
A 55 year-old female with
hemoptysis. |
Well- differentiated fetal type adenocarcinoma associated
with angiolymphatic and visceral pleural invasion. |
|
|
J0 |
U |
A woman in her 70s with a double
lung transplant. |
Pulmonary alveolar microlithiasis. |
|
|
J0 |
U |
A 77 year-old man with worsening
dyspnea. |
Diffusely infiltrating, moderately differentiated left lung
primary adenocarcinoma, diffuse interstitial pulmonary fibrosis/usual
interstitial pneumonia. |
|
|
J0 |
U |
A caucasian woman in her late 20s
with progressive shortness of breath. |
Granulomatous pneumonitis secondary to sarcoidosis. |
|
|
J0 |
U(P) |
A neonate with spontaneous
pneumothorax and progressive respiratory failure. |
Alveolar capillary dysplasia with misalignment of pulmonary
veins. |
|
|
J0 |
X |
A 35 year-old woman with a history
of arthralgia and myalgia. |
Mixed connective tissue disease with pulmonary fibrosis,
secondary pulmonary hypertension and hyaline membrane disease. |
|
|
K0 |
G(P) |
A 7 month-old baby with an
incidental testicular tumor and congenital nephrotic syndrome. |
Denys-Drash syndrome. Dysgenetic testis with juvenile
granulosa cell tumor. Blastematous Wilms tumor in right kidney, and
nephroblastematosis. |
|
|
K0 |
TN |
A woman in her 70s with a clear
cell renal mass. |
Clear cell papillary renal cell carcinoma. |
|
|
K1 |
G(P) |
A female fetus with bilateral
multicystic kidneys. |
Fatty acid oxidation disorder, most likely glutaric acidemia
type II. |
|
|
K1 |
TC |
A 39-year-old female with a
complex renal cyst. |
Angiomyolipoma with epithelial cysts. |
|
|
K1 |
TM |
A 60 year-old woman with breast
cancer and a left renal mass. |
Conventional (clear) renal cell carcinoma with metastatic
breast carcinoma within renal cell carcinoma and within non-neoplastic
renal parenchyma. |
|
|
K1 |
TN |
A female in her 80s with a renal
mass. |
Clear cell papillary renal cell carcinoma |
|
|
K1 |
TN |
A 52-year-old female with flank
pain, hematuria, and cirrhosis. |
Collecting duct carcinoma. |
|
|
K1 |
TN |
A 51-year-old woman with chronic
fatigue and weakness. |
Neuroendocrine carcinoma of the kidney. |
|
|
K1 |
TN |
A 69 year-old female with a renal
mass. |
Renal cell carcinoma with features of clear cell papillary
subtype. |
|
|
K1 |
TN |
A 62 year-old man with an
unexplained 60 lb weight loss. |
Glomus tumor of the kidney. |
|
|
K1 |
TN |
A 69-year-old male with a renal
mass. |
High-grade neuroendocrine carcinoma. |
|
|
K1 |
TN |
A 60 year-old woman with breast
cancer and a left renal mass. |
Conventional (clear) renal cell carcinoma with metastatic
breast carcinoma within renal cell carcinoma and within non-neoplastic
renal parenchyma. |
|
|
K1 |
TN |
A man in his 70s with nausea and
vomiting. |
Renal cell carcinoma. |
|
|
K1 |
TN |
A 74 year-old man with right flank
pain. |
Chromophobic renal cell carcinoma. |
|
|
K1 |
TN(P) |
A 19 month-old boy with a renal
mass. |
Clear cell sarcoma of the kidney, stage 3 (renal hilar node
involvement). |
|
|
K1 |
TN |
A 68 year-old female with a large
mass in the right kidney. |
Clear cell renal cell carcinoma with multifocal
angiomyolipoma with the kidney and perinephric lymph nodes. |
|
|
K1 |
TN |
A 69 year-old female with a
renal mass. |
Clear cell renal cell carcinoma with associated
juxtaglomerular tumor. Nodular hyperplasia of the adrenal gland. |
|
|
K1 |
TN(P) |
A 7 month-old baby with an
incidental testicular tumor and congenital nephrotic syndrome. |
Denys-Drash syndrome. Dysgenetic testis with juvenile
granulosa cell tumor. Blastematous Wilms tumor in right kidney, and
nephroblastematosis. |
|
|
K2 |
TN |
A woman in her 70s with a bladder
mass. |
Clear cell adenocarcinoma associated with nephrogenic
adenoma, adenocarcinoma in situ, intestinal metaplasia and lymph node
involvement by endosalpingiosis. |
|
|
K2 |
TN |
A 34 year-old man with abdominal
pain and dysuria. |
Urachal adenocarcinoma associated with villous adenoma. |
|
|
K2 |
TN |
A 94 year-old man with a bladder
mass. |
Invasive urothelial carcinoma with predominant sarcomatoid
differentiation. |
|
|
K2 |
TN |
An 82 year-old woman with
right-sided hydronephrosis. |
High-grade urothelial carcinoma with plasmacytoid,
micropapillary and glandular differentiation. |
|
|
K2 |
TS |
A woman in her 70s with a bladder
mass. |
Clear cell adenocarcinoma associated with nephrogenic
adenoma, adenocarcinoma in situ, intestinal metaplasia and lymph node
involvement by endosalpingiosis. |
|
|
K3 |
G |
A man in his 20s with proteinuria
and deafness. |
X-linked Alport syndrome |
|
|
K3 |
G |
Renal insufficiency in a 68
year-old woman. |
Fabry Disease - mosaic pattern. |
|
|
K3 |
G |
A 36-year-old female with
microalbuminuria. |
Renal involvement by Fabry disease. |
|
|
K3 |
G |
A 32 year-old male with recurrent
fevers of unknown origin. |
Fabry's disease. |
|
|
K3 |
I |
A 21 year-old male with
acute renal failure. |
Post-infectious glomerulonephritis with IgA predominance. |
|
|
K3 |
I |
A 30-year-old woman with nephrotic
syndrome. |
Membranoproliferative glomerulonephritis, type-III (Strife
variant). |
|
|
K3 |
I |
A 42-year-old man with weakness,
fatigue and edema of the face and extremities. |
Parvovirus B19-related glomerulonephritis. |
|
|
K3 |
I |
A 31 year-old male status-post
kidney transplant with increased creatinine. |
BK virus nephropathy with diffuse tubular basement membrane
C4d staining. |
|
|
K3 |
I |
A 62 year-old male with flank pain
and hematuria. |
Diffuse anti-basement membrane antibody glomerulonephritis
with cellular crescents. |
|
|
K3 |
I |
A 74 year-old man with a history
of scleroderma and recent rapidly progressive renal insufficiency. |
Immunotactoid glomerulonephritis. |
|
|
K3 |
I |
A 73 year-old man with acute renal
failure. |
Wegener’s granulomatosis. |
|
|
K3 |
TH |
A 71 year-old man with acute renal
failure. |
Waldenstrom's macroglobulinemia with advanced amyloidosis,
atypical, monoclonal lymphoplasmacytic interstitial infiltrate with
admixed reactive T-lymphocytes; consistent with renal interstitial
involvement by lymphoplasmacytic lymphoma. |
|
|
K3 |
U |
An 18 year-old male with
microscopic hematuria. |
Early dense deposit disease (membranoproliferative
glomerulonephritis type II) |
|
|
K3 |
U |
A 31 year-old male status-post
kidney transplant with increased creatinine. |
BK virus nephropathy with diffuse tubular basement membrane
C4d staining. |
|
|
K3 |
U |
A 65 year-old woman with renal
insufficiency. |
Advanced amyloidosis and chronic secondary ischemia with
marked chronicity changes. |
|
|
K3 |
U |
A 68 year-old male with renal
insufficiency. |
Diffuse fibrillary glomerulopathy. |
|
|
L0 |
TM |
A 75 year-old male with
obstructive jaundice and a pancreatic head mass- with FNA. |
Metastatic prostatic adenocarcinoma. |
|
|
L1 |
I |
An unusual cause of liver failure
leading to liver transplantation. |
HAV associated hepatic failure with unusual presentation. |
|
|
L1 |
I(C) |
A 35 year-old man with jaundice
and weight loss-FNA. |
Cholangiocarcinoma, secondary to infection of liver flukes (Clonorchis
sinensis or Opisthorchis
viverrini). |
|
|
L1 |
I(P) |
A post-transplant teenager with
liver lesion. |
EBV-associated smooth muscle tumor. |
|
|
L1 |
T1 |
A 72 year-old woman with a history
of cirrhosis secondary to alcohol abuse and hepatitis c. |
Cholangiocarcinoma arising in a HCV related cirrhotic liver. |
|
|
L1 |
TC |
A 61 year-old male with a cystic
pancreatic mass. |
Cystic schwannoma. |
|
|
L1 |
TN(C) |
A 35 year-old man with jaundice
and weight loss-FNA. |
Cholangiocarcinoma, secondary to infection of liver flukes (Clonorchis
sinensis or Opisthorchis
viverrini). |
|
|
L1 |
TN(C) |
An 81-year-old man with multiple
liver masses-FNA. |
Metastatic gastrointestinal stromal tumor (GIST),
epithelioid type. |
|
|
L1 |
TN(C) |
A 10 year-old girl with a hepatic
Epstein-Barr virus-associated smooth muscle tumor. |
Chronic myelogenous leukemia, chornic phase,
BCR-ABL1 positive. |
|
|
L1 |
TN(C) |
A 10 year-old girl with a hepatic
Epstein-Barr virus-associated smooth muscle tumor. |
Chronic myelogenous leukemia, chornic phase,
BCR-ABL1 positive. |
|
|
L1 |
TN(P) |
A post-transplant teenager with
liver lesion. |
EBV-associated smooth muscle tumor. |
|
|
L1 |
TN(P) |
A 2-year-old girl with a liver
mass. |
Well-differentiated fetal hepatoblastoma. |
|
|
L1 |
TN(P) |
A 2 year-old girl with right upper
quadrant mass. |
Yolk sac tumor arising in a mature teratoma of the liver. |
|
|
L1 |
TS |
A 48-year-old woman with a
one-year history of back pain. |
Focal nodular hyperplasia lesions of liver. |
|
|
L3 |
F |
A 79-year-old male with a lesion
in the head of the pancreas. |
Post-operative spindle cell nodule, with associated suture
granuloma and traumatic neuroma, focal pancreatic intraepithelial
neoplasia PanIN II. |
|
|
L3 |
I |
Jaundice in a 60 year-old female. |
Type 1 autoimmune pancreatitis. |
|
|
L3 |
I |
A 67 year-old female with a distal
pancreatic mass. |
Type 1 autoimmune pancreatitis (IgG4 sclerosing disease). |
|
|
L3 |
TN |
A 68-year-old woman with a right
parotid mass. |
Low-grade cribriform cystadenocarcinoma (aka. "low-grade
salivary duct carcinoma") |
|
|
L3 |
TN |
A 79-year-old male with a lesion
in the head of the pancreas. |
Post-operative spindle cell nodule, with associated suture
granuloma and traumatic neuroma, focal pancreatic intraepithelial
neoplasia PanIN II. |
|
|
L3 |
TN |
A man in his 70s with right upper
quadrant and left-sided back pain. |
Clear cell pancreatic adenocarcinoma. |
|
|
L3 |
TN |
A male his 40s with a pancreatic
mass. |
Acinar cell carcinoma of the pancreas. |
|
|
L3 |
TN |
A 56 year-old female with a
pancreatic mass. |
Pancreatic neuroendocrine carcinoma with
solid-pseudopapillary features. |
|
|
L3 |
TN |
A 72-year-old man with a distal
pancreatic mass. |
Pancreatic islet cell tumor. |
|
|
M0 |
TC |
A 57 year-old female with an
anterior mediastinal mass. |
Thymic carcinoid. |
|
|
M0 |
TH |
A male in his 30s with a
mediastinal mass. |
Mediastinal B-cell lymphoma. |
|
|
N0 |
F(P) |
A teenager male with a brain mass. |
Diffuse large b- cell lymphoma, monomorphic, Post
transplantation lymphoproliferative disorder (PTLD). |
|
|
N0 |
I |
A woman in her 60's with an
abnormal brain MRI an abnormal brain MRI. |
Toxoplasmosis |
|
|
N0 |
I |
A 38 year-old male with multiple
brain masses. |
Acute demyelinating disease. |
|
|
N0 |
I |
A 58 year-old male with fevers,
cutaneous nodules and cerebrovascular accident. |
Disseminated
Scedosporium prolificans (inflatum) infection. |
|
|
N0 |
I |
A 38 year-old kidney transplant
patient with progressive mental status change. |
Granulomatous amoebic encephalitis due to
Acanthamoeba castellanii. |
|
|
N0 |
I |
A 44 year-old woman with new brain
lesion. |
Acute demyelinating lesion consistent with multiple
sclerosis. |
|
|
N0 |
TC(P) |
A preadolescent female with a
series of neurological symptoms. |
Neurenteric Cyst |
|
|
N0 |
TH |
A man in his 50s with acute onset
aphasia and right sided weakness. |
Intravascular lymphoma, large B-cell type. |
|
|
N0 |
TH |
A 44 year-old HIV positive man
died following bleeding from mouth and nose. |
Disseminated
Mycobacterium avium complex infection, disseminated
Klebsiella pneumoniae
infection, central nervous system lymphoma and extensive hemorrhage. |
|
|
N0 |
TH(P) |
A teenager male with a brain mass. |
Diffuse large b- cell lymphoma, monomorphic, Post
transplantation lymphoproliferative disorder (PTLD). |
|
|
N0 |
TN |
A woman in her 50s with a cervical
spinal tumor. |
Melanocytoma. |
|
|
N0 |
TN |
A 79 year-old female with a cauda
equina tumor. |
Myxopapillary ependymoma, WHO grade I. |
|
|
N0 |
TN |
A 43 year-old man with back pain
and a spinal mass. |
Paraganglioma with extensive gangliocytic differentiation. |
|
|
N0 |
TN |
An 18-year-old female with a brain
mass. |
Pleomorphic xanthoastrocytoma. |
|
|
N0 |
TN |
A 38-year-old man with a nodular
brain mass. |
Recurrent oligodendroglioma. |
|
|
N0 |
TN |
A 57 year-old woman with a
cerebellar mass. |
Lhermitte-Duclos disease (dysplastic gangliocytoma of the
cerebellum). |
|
|
N0 |
TN |
A 60-year-old man with a history
of headaches. |
Calcifying pseudoneoplasm of the neuraxis in association
with a ganglioglioma. |
|
|
N0 |
TN |
A male in his 70s with a brain
mass. |
Meningioma, secretory variant. |
|
|
N0 |
TN |
A lady in her 20s with a history
of upper extremity numbness and weakness. |
Hemangioblastoma. |
|
|
N0 |
TN |
A 27-year-old female with
anaplastic ependymoma. |
Anaplastic ependymoma (WHO grade III/IV). |
|
|
N0 |
TN |
A 48 year-old woman with new onset
diplopia and mental status changes. |
Pineoblastoma. |
|
|
N0 |
TN(P) |
Posterior fossa mass in a two
month-old female. |
Polar spongioblastoma with focal pilocytic astrocytoma
differentiation. (Note: polar spongioblastoma was included in the WHO
1979 classification but had since been removed. It is not recognized
currently as a distinct entity). |
|
|
N0 |
TN(C) |
Intraventricaular mass in a 4
year-old girl. |
Subependymal giant cell astrocytoma. |
|
|
N0 |
TN(P) |
A 13-year-old girl with a history
of frequent headaches. |
Subependymal giant cell astrocytoma. |
|
|
N0 |
U |
A 27-year-old male with
deteriorating levels of consciousness. |
Acute Wernicke-type encephalopathy |
|
|
N0 |
U |
A 60-year-old man with a history
of headaches. |
Calcifying pseudoneoplasm of the neuraxis in association
with a ganglioglioma. |
|
|
N0 |
U(P) |
A 13-year-old boy with
neurodegeneration. |
Neuronal intranuclear inclusion disease, juvenile-sporadic. |
|
|
N1 |
I |
A 56 year-old woman with left
facial numbness. |
Sural nerve: Axonal degeneration with non-caseating
granulomas and vasculitis. Medial gastrocnemius muscle: Granulomatous
myositis. |
|
|
O0 |
G(P) |
A baby girl with a bulging eye. |
Plexiform neurofibroma of the orbit, melanocytic nevus of
the iris (lisch nodule), diffuse uveal hamartoma with neural and
melanocytic elements, buphthalmos, anterior peripheral synechiae,
retinal degeneration affecting predominantly the ganglion cell layer,
cupping of the optic nerve head, cataractous lens. |
|
|
O0 |
TN(P) |
A baby girl with a bulging eye. |
Plexiform neurofibroma of the orbit, melanocytic nevus of
the iris (lisch nodule), diffuse uveal hamartoma with neural and
melanocytic elements, buphthalmos, anterior peripheral synechiae,
retinal degeneration affecting predominantly the ganglion cell layer,
cupping of the optic nerve head, cataractous lens. |
|
|
P0 |
TH |
A 51 year-old female with morbid
obesity and abdominal pain, severe constipation and thirst. |
B-cell lymphoid neoplasm with high-grade features (abdominal
lymphomatosis) |
|
|
P0 |
TN |
A 53-year-old man with abdominal
distention. |
Pseudomyxoma peritonei, peritoneal mucinous carcinomatosis
of presumed appendiceal origin. |
|
|
P0 |
TN |
A 55 year-old woman with solitary
fibrous tumor of the pleura. |
Solitary fibrous tumor (localized fibrous tumor) of the
pleura. |
|
|
Q0 |
C(P) |
A 13 year-old female with a
unilateral neck mass. |
Cervical thymic cyst. |
|
|
R0 |
TC |
A 31-year-old female with a right
upper quadrant cyst. |
Vascular adrenal cyst. |
|
|
R0 |
TN |
A man in his 70s with nausea and
vomiting. |
Renal cell carcinoma. |
|
|
R0 |
TN |
A 71 year-old woman with an
adrenal mass. |
Corticomedullary tumor with elements of pheochromocytoma and
adrenocortical adenoma. |
|
|
R0 |
TN |
A 63 year-old woman with
right-sided mass involving kidney and liver. |
Adrenal cortical carcinoma with direct extension into the
liver. |
|
|
R0 |
TN |
Retroperitoneal masses in a 45
year-old man and a 42 year-old woman. |
Case 1: Extraadrenal Paraganglioma. Case 2: Malignant
Extraadrenal Paraganglioma with metastasis to the lesser curvature of
the stomach and one right sacral neural foramina lymph node. |
|
|
R0 |
TS |
A 69 year-old female with a
renal mass. |
Clear cell renal cell carcinoma with associated
juxtaglomerular tumor. Nodular hyperplasia of the adrenal gland. |
|
|
S0 |
F(P) |
A 20 month-old girl with a left
calf mass. |
Alveolar rhabdomyosarcoma with treatment-induced
cytodifferentiation. |
|
|
S0 |
F |
An 80-year-old man with a right
paratesticular mass. |
Paratesticular angiosarcoma following radiation therapy for
prostatic adenocarcinoma. |
|
|
S0 |
G |
A 30 year-old female with a
painful left index finger. |
Intra-osseous and soft tissue granulomatous reaction
compatible with gout. |
|
|
S0 |
I(C) |
A 10 year-old girl with a hepatic
Epstein-Barr virus-associated smooth muscle tumor. |
Chronic myelogenous leukemia, chornic phase,
BCR-ABL1 positive. |
|
|
S0 |
TH |
A 65 year-old woman with malignant
lymphoma. |
Malignant lymphoma, small B-cell type with plasmacytic
differentiation and crystal-storing histiocytosis. |
|
|
S0 |
TM |
A 47 year-old woman with a thigh
mass. |
Follicular thyroid carcinoma arising in
struma
ovarii with metastasis to the thigh. |
|
|
S0 |
TN |
Young male with soft tissue mass
of ankle. |
Pseudomyogenic hemangioendothelioma. |
|
|
S0 |
TN |
A 24 year-old female with gradual
onset of abdomen pain. |
Synovial sarcoma. |
|
|
S0 |
TN |
A 52 year-old male with a 3 week
history of abdominal pain. |
Leiomyosarcoma, myxoid variant. |
|
|
S0 |
TN |
A 42 year-old woman with a
posterior knee mass. |
High-grade sarcoma with features of myxofibrosarcoma. |
|
|
S0 |
TN |
A 52 year-old female with
intermittent left facial paresthesia/hyperesthesia and swelling. |
Malignant solitary fibrous tumor. |
|
|
S0 |
TN |
A 39 year-old female with right
forearm lesion. |
Neurothekeoma. |
|
|
S0 |
TN |
A 57 year-old male with a pelvic
mass. |
Aggressive angiomyxoma with focal marked vascular smooth
muscle proliferation. |
|
|
S0 |
TN |
A 17-year-old female with a
subcutaneous left thigh mass. |
Angiomatoid fibrous histiocytoma. |
|
|
S0 |
TN(P) |
A 20-month-old girl with a left
calf mass. |
Alveolar rhabdomyosarcoma with treatment-induced
cytodifferentiation. |
|
|
S0 |
TN |
A female in her 30s with a right
iliac fossa mass. |
High-grade sarcoma, favoring malignant peripheral nerve
sheath tumor (MPNST). |
|
|
S0 |
TN |
A male in his 20s with multiple
"atypical" nevi. |
Atypical melanocytic neoplasms of uncertain malignant
potential. |
|
|
S0 |
TN |
A 67 year-old man with progressive
shortness of breath. |
Rhabdomyosarcoma of pulmonary artery trunk. |
|
|
S0 |
TN |
A 30-year-old male with a mass in
the right ischial rectal fossa. |
Synovial sarcoma. |
|
|
S0 |
TN |
A 59-year-old woman with a nodule
in the right breast. |
Myofibroblastoma, epithelioid type. |
|
|
S0 |
TN |
A 43-year-old obese female with
vague left hip discomfort and low back pain. |
Primary low-grade leiomyosarcoma of left ilium. |
|
|
S0 |
TN(P) |
A 19 month-old boy with a renal
mass. |
Clear cell sarcoma of the kidney, stage 3 (renal hilar node
involvement). |
|
|
S0 |
TN |
A 62 year-old man with a left
supraclavicular mass. |
Palisaded myofibroblastoma (intranodal hemorrhagic
spindle-cell tumor with "amianthoid" fibers). |
|
|
S0 |
TN |
A 67 year-old female with skin
lesion. |
Cutaneous leiomyosarcoma. |
|
|
S0 |
TN(C) |
A man in his early 20s with a mass
on the lateral aspect of his right lower leg-with FNA. |
Schwannoma. |
|
|
S0 |
TN(P) |
A 7-month-old male with a 4.5 cm
deep left inner thigh lesion. |
Kaposiform hemangioendothelioma. |
|
|
S0 |
U |
A 74-year-old man with a right
thigh mass. |
Extranodal Rosai-Dorfman disease. |
|
|
S0 |
U |
A 44 year-old white male with a
left flank mass. |
Diffuse angiomatosis (angiomatosis of soft tissue, diffuse
hemangioma). |
|
|
S0 |
U(P) |
A 9½
year-old boy with pain in left
proximal medial thigh. |
Myositis ossificans. |
|
|
T1 |
C(P) |
A 14 year-old boy with congenital
hypothyroidism. |
Dyshormonogenetic goiter. |
|
|
T1 |
I |
A female in her 20s with a thyroid
mass. |
Papillary thyroid carcinoma, diffusely involving both
thyroid lobes, background thyroid with severe chronic lymphocytic
thyroiditis in a follicular destructive pattern. |
|
|
T1 |
TH |
A female in her 20s with a thyroid
mass. |
Papillary thyroid carcinoma, diffusely involving both
thyroid lobes, background thyroid with severe chronic lymphocytic
thyroiditis in a follicular destructive pattern. |
|
|
T1 |
TH |
A 65 year-old female with right
neck mass. |
Follicular dendritic cell tumor involving thyroid and right
cervical lymph nodes. |
|
|
T1 |
TM |
65 year-old man with an enlarged
thyroid-FNA. |
Metastatic renal cell carcinoma. |
|
|
T1 |
TN |
A 57 year-old female with an
actively growing right neck mass. |
Anaplastic thyroid carcinoma. |
|
|
T1 |
TN |
A 69-year-old man presented with a
left neck mass. |
Papillary carcinoma, hyalinizing trabecular tumor,
multinodular thyroid. |
|
|
T1 |
TN |
A 68 year-old female with an
incidental thyroid cyst. |
Rhabdoid (anaplastic) thyroid carcinoma associated with
and/or arising from a papillary thyroid carcinoma. |
|
|
T1 |
TN |
A 66 year-old male with a left
thyroid mass. |
Moderately differentiated medullary carcinoma of the
thyroid. |
|
|
T1 |
TN |
A 55 year-old male with neck mass. |
Well differentiated Hürthle cell carcinoma with focal
degeneration. |
|
|
T1 |
TN |
An 80 year-old female with a
neck mass. |
Poorly differentiated "insular" thyroid carcinoma. |
|
|
T1 |
TN(C) |
A 58 year-old woman with a thyroid
nodule-with FNA. |
Suspicious for non-Hodgkin Lymphoma. |
|
|
U0 |
TH |
A 49 year-old male with headache
and diplopia. |
Plasma cell neoplasm -
kappa light chain restricted. |
|
|
U0 |
TN |
A man in his 20s with a sudden
onset of polydipsia and polyuria. |
Germinoma. |
|
|
V0 |
I |
A 56 year-old woman with left
facial numbness. |
Sural nerve: Axonal degeneration with non-caseating
granulomas and vasculitis. Medial gastrocnemius muscle: Granulomatous
myositis. |
|
|
V0 |
I |
A 52 year-old woman with
gastrointestinal bleeding and a history of rheumatoid arthritis. |
Necrotizing leukocytoclastic small vessel vasculitis of the
colon, of probable autoimmune etiology. |
|
|
V0 |
I |
A 73 year-old man with acute renal
failure. |
Wegener’s granulomatosis. |
|
|
W0 |
G |
An 87-year-old male with a
pathologic hip fracture. |
Paget’s disease of bone associated with secondary
osteosarcoma of femur invading surrounding soft tissue. |
|
|
W0 |
G |
A 30 year-old female with a
painful left index finger. |
Intra-osseous and soft tissue granulomatous reaction
compatible with gout. |
|
|
W0 |
G(P) |
A 17 weeks fetus with significant
shortening of long bones. |
Osteogenesis imperfecta Type II (OI II). |
|
|
W0 |
TH |
A 41 year man with sharp pain in
the right side of his rib cage. |
Langerhans cell histiocytosis. |
|
|
W0 |
TH |
A male in his 60s with plasma cell
neoplasm, favor solitary plasmacytoma of bone. |
Plasma cell neoplasm, favor solitary plasmacytoma of bone. |
|
|
W0 |
TM |
Adult male with a lytic temporal
bone lesion. |
Metastatic acinic cell carcinoma from salivary gland with
high-grade transformation |
|
|
W0 |
TM |
A woman presented with severe back
pain and lytic lesions in lumbar spine and a pelvic mass. |
Primitive neuroectodermal tumors/Ewing sarcoma. |
|
|
W0 |
TM |
A 75 year-old female with a
history of treated urothelial carcinoma. |
Metastatic urothelial carcinoma to the calcaneus. |
|
|
W0 |
TN |
Middle age female with a femur
lesion. |
Liposclerosing myxofibrous tumor |
|
|
W0 |
TN |
An 80 year-old man with a palpable
groin mass. |
Dedifferentiated chondrosarcoma. |
|
|
W0 |
TN |
An 86 year-old woman with a
sacrococcygeal mass-FNA. |
Chordoma. |
|
|
W0 |
TN |
An 87-year-old male with a
pathologic hip fracture. |
Paget’s disease of bone associated with secondary
osteosarcoma of femur invading surrounding soft tissue. |
|
|
W0 |
TN |
A 43-year-old obese female with
vague left hip discomfort and low back pain. |
Primary low-grade leiomyosarcoma of left ilium. |
|
|
W0 |
TN |
A 19 year-old man with progressive
low back pain. |
Ewing sarcoma, PNET. |
|
|
W0 |
TN |
A 67 year-old man with a lytic and
blastic lesion of left tibia. |
Dedifferentiated chondrosarcoma. |
|
|
W0 |
TN |
A 60 year-old man with coccygeal
mass. |
Chordoma with focal chondroid features. |
|
|
W0 |
TN |
A 20 month-old old male with left
paravertebral mass. |
Yolk sac tumor. |
|
|
X |
G(P) |
5-month-old twins with
turricephaly. |
Peroxisome biogenesis disorder, clinically consistent with
Zellweger syndrome. |
|
|
X0 |
G(P) |
A 24-day-old term infant with
seizures. |
DiGeorge syndrome, transfusion related graft versus host
disease, and multiorgan failure with disseminated intravascular
coagulation. |
|
|
X0 |
I |
A 35 year-old transplant recipient
with fevers and mental status changes. |
Disseminated toxoplasmosis. |
|
|
X0 |
I |
A 44 year-old HIV positive man
died following bleeding from mouth and nose. |
Disseminated
Mycobacterium avium complex infection, disseminated
Klebsiella pneumoniae
infection, central nervous system lymphoma and extensive hemorrhage. |
|
|
X0 |
I(P) |
Complete heart block in a 9
year-old boy status post small bowel and kidney transplants. |
Disseminated fungal sepsis. |
|
|
X0 |
TH |
A 24 year-old man with end-stage
restrictive lung disease and liver disease. |
Langerhans Cell Histocytosis. |
|
|
X0 |
TM |
A transplant patient with multiple
cutaneous malignancies and related fatal outcome. |
Merkel cell carcinoma with metastases to liver, skin, bone
marrow of rib, mesenteric lymph nodes, diaphragm, pancreas, and adrenal
gland. |
|
|
X0 |
TM |
Ovarian mass in a woman at her 50s
with endometriosis. |
Clear cell carcinoma of right ovary with endometrioid and
papillary features, sigmoid colon and omentum positive for metastatic
carcinoma, right fallopian tube, sigmoid colon, left ovary, and appendix
with endometriosis. |
|
|
X0 |
TM |
Retroperitoneal masses in a 45
year-old man and a 42 year-old woman. |
Case 1: Extraadrenal Paraganglioma. Case 2: Malignant
Extraadrenal Paraganglioma with metastasis to the lesser curvature of
the stomach and one right sacral neural foramina lymph node. |
|
|
X0 |
TN |
A 75-year-old male with abdominal
distension, weakness and anemia. |
Sarcoma, suspect recurrent malignant gastrointestinal
stromal tumor with extensive peritoneal metastases. |
|
|
X0 |
U |
A 24-year-old man with flu-like
symptoms. |
Polyglandular autoimmune syndrome type II (Schmidt
syndrome). |
|
|
X0 |
X |
A 35 year-old woman with a history
of arthralgia and myalgia. |
Mixed connective tissue disease with pulmonary fibrosis,
secondary pulmonary hypertension and hyaline membrane disease. |
|
|
Z0 |
G |
A 42 year-old male with nevoid
basal cell carcinoma syndrome. |
Nevoid basal cell carcinoma syndrome (Gorlin syndrome). |
|
|
Z0 |
G |
A 38 year-old female with
phrynoderma following gastric bypass surgery. |
Focal parakeratosis consistent with phrynoderma (vitamin a
deficiency). |
|
|
Z0 |
G(P) |
Abdominal skin lesion and mass in
a newborn. |
Neurocutaneous melanocytosis, with a giant congenital
melanocytic nevus with neurotization, and a deep proliferative nodule. |
|
|
Z0 |
I |
A 53-year-old male with a five-day
history of worsening rash, pain and swelling in his right hand. |
Neutrophilic dermatosis. |
|
|
Z0 |
I |
A 67 year-old post-transplant
patient with cutaneous nodules and ulcers. |
Necrotizing granulomatous dermatitis, secondary to
Scedosporium apiospermum. |
|
|
Z0 |
TC |
A 53 year-old man presented with
a cyst on his left cheek. |
Steatocystoma. |
|
|
Z0 |
TH |
A 61-year-old female with a mass
in the right supraclavicular area. |
Non-Hodgkin lymphoma, peripheral T-cell type, with features
of ALK-1 negative anaplastic large cell lymphoma. |
|
|
Z0 |
TH |
A 76 year-old woman with a left
thigh mass |
Primary cutaneous follicle center lymphoma. |
|
|
Z0 |
TH |
A 74 year-old female with inflamed
"seborrheic keratosis" on dorsum of right ankle. |
Malignant melanoma, in
situ and invasive. |
|
|
Z0 |
TH(P) |
A 7 year-old boy with multiple
skin lesions. |
CD30 positive lymphoproliferative disorder of the skin. |
|
|
Z0 |
TN(P) |
A teenager female with a neck
mass. |
Eccrine spiradenoma |
|
|
Z0 |
TN |
A 70 year-old male with a mass on
the right thigh. |
Pilomatrix carcinoma of the skin and soft tissue arising on
the right thigh with metastases to three right groin lymph nodes. |
|
|
Z0 |
TN |
A 69-year-old woman with a groin
mass. |
Merkel cell carcinoma. |
|
|
Z0 |
TN |
A 39 year-old female with right
forearm lesion. |
Neurothekeoma. |
|
|
Z0 |
TN |
An elderly man with a plaque-like
crusted lesion of his right temple. |
Cutaneous neuroendocrine carcinoma (Merkel cell carcinoma)
arising in association with basal cell carcinoma and squamous cell
carcinoma in-situ of skin with metastasis to supraclavicular lymph nodes
involved by chronic lymphocytic leukemia/small lymphocytic lymphoma. |
|
|
Z0 |
TN |
A young woman with an unusual
"cyst". |
Atypical spindle cell neoplasm, compatible with malignant
melanoma, desmoplastic / neurotropic type. |
|
|
Z0 |
TN |
A 67 year-old female with skin
lesion. |
Cutaneous leiomyosarcoma. |
|
|
Z0 |
TN |
A 42 year-old male with nevoid
basal cell carcinoma syndrome. |
Nevoid basal cell carcinoma syndrome (Gorlin syndrome). |
|
|
Z0 |
TN |
A 69 year-old male with pigmented
lesion on his right ear. |
Lentigo maligna (Atypical Lentiginous Hyperplasia). |
|
|
Z0 |
TN |
A 54 year-old male with a right
cheek mass. |
Squamous cell carcinoma. |
|
|
Z0 |
TN |
A 79 year-old male with
frontal headaches. |
Coexistent inverted papilloma and verrucous carcinoma. |
|
|
Z0 |
TN(P) |
Abdominal skin lesion and mass in
a newborn. |
Neurocutaneous melanocytosis, with a giant congenital
melanocytic nevus with neurotization, and a deep proliferative nodule. |
|
|
Z0 |
TS |
A 74 year-old female with inflamed
"seborrheic keratosis" on dorsum of right ankle. |
Malignant melanoma, in
situ and invasive. |
|
|
Z0 |
TS |
A 64-year-old female with left
nipple discharge and an inverted nipple. |
Paget's disease of the breast. |
|
|
Z0 |
U(P) |
A 2 year-old girl with skin lesion
on right arm. |
Juvenile xanthogranuloma. |