Anatomic Pathology Case of the Month

Univeristy of Pittsburgh Medical Center (UPMC)

Listed by site and type with diagnosis.

Sorted by chronological order  Sorted without diagnosis  Show the codes in a separate window

 

 Site Code

 

A0:   Alimentary canal

F0:    Female genital system

L0:    Hepatobiliary tract & pancreas

  A1: Esophagus

  F1:  Female external genitalia

  L1:  Liver

  A2: Stomach

  F2:  Vagina

  L2:  Gallbladder & extrahepatic biliary track

  A3: Duodenum

  F3:  Uterine cervix

  L3:  Pancreas

  A4: Small intestine  

  F4:  Uterine corpus & soft tissue

M0:  Mediastinum & thymus

  A5: Appendix

  F5:  Fallopian tube

N0:   Central nervous system

  A6: Colon & cecum

  F6:  Ovary

 N1:  Nerve & muscle biopsy

  A7: Rectum and anus

  F7:  Placenta and trophoblasts

O0:   Eye & orbit

B0:   Breast & skin of breast

G0:   Male genital system

P0:    Pleura, peritoneum, mesentery, & omentum

C0:   Cardiovascular system

  G1: Testis & related structures

Q0:   Head & neck, miscellaneous

  C1: Heart

  G2: Prostate & seminal vesicles

R0:    Adrenal & paraganglia

  C2: Major blood vessels

  G3: Penis & related structures

S0:    Soft tissue & peripheral nerve (surgical)

D0:   Oral cavity, mandible, & maxilla

H0:   Bone marrow, lymph nodes & spleen

T0:    Thyroid & parathyroid

  D1: Mucosa, soft tissue, & tongue

I0:     Larynx & upper respiratory tract

  T1:  Thyroid

  D2: Mandible & maxilla

J0:     Lung & lower respiratory tract

  T2:  Parathyroid

E0:    Major salivary glands

K0:    Urinary system & adrenal

U0:   Pituitary gland & sellar area

 

 K1:   Kidney, surgical

V0:   Small blood vessels & lymphatics

 

 K2:   Ureter, bladder, urachus, & urethra

W0:  Bone & joint

 

 K3:   Kidney, medical

X0:    Miscellaneous & unclassified

 

 

Z0:    Skin

 

Type  Code

C-            Congenital malformation

D-           Neurodegenerative disease

F-            Forensic, intoxication, iatrogenic, & medication related

G-           Genetic and/or metabolic

I-             Infection, inflammation, & demyelination

TC-          Neoplastic & non-neoplastic cyst (grossly cystic)

TH-         Neoplasm, hematopoietic, histiocytic, & dendritic

TM-        Metastasis

TN-         Neoplasm & solid tumor-like lesions

TS-          Hyperplasia, dysplasia, in situ neoplasm

U-           Unclassified or mixed

(P)-         Pediatric & perinatal
(C)-         Cytology

 

Site

Type

Case Number

Clinical information

Diagnosis

A0

U

UPMC-2014-04-0823

A 6 year-old female transplant patient presents with fever and rectal bleeding.

Malakoplakia of allograft gastrointestinal tract including stomach, ileum, and colon and native colon.

A0

U

UPMC-2004-01-0375

A woman in her 40s with endometriosis and bland glandular inclusions.

Endometriosis of ileocecal junction, focal endometriosis in two of seventeen lymph nodes, bland glandular inclusions in two of seventeen lymph nodes.

A0

C(P)

UPMC-2016-12-0923

A child with hirschsprung disease.

Total intestinal aganglionosis with a segment of dysganglionosis in the submucosa of proximal jejunum

A1

TN

UPMC-2014-02-0813

A 46 year-old female with a nodule at the mid esophagus.

Esophageal granular cell tumor associated with pseudoepitheliomatous hyperplasia.

A1

TS

UPMC-2014-02-0813

A 46 year-old female with a nodule at the mid esophagus.

Esophageal granular cell tumor associated with pseudoepitheliomatous hyperplasia.

A2

I

UPMC-2019-04-1023

Gastric biopsy from man in his 40's - can AI make the diagnosis?

Helicobacter pylori gastritis

A2

I

UPMC-2007-09-0526

An 18-year-old woman with abdominal pain.

Intense gastritis with reactive lymphoid infiltrate compatible with Epstein-Barr virus related gastritis.

A2

I

UPMC-1999-06-0196

A 64-year-old woman with a long history of irritable bowel syndrome.

Poorly differentiated gastric adenocarcinoma with metastatic disease involving the colon arising in a background of chronic active gastritis with incomplete intestinal metaplasia with heavy colonization by Helicobacter pylori.

A2

TN

UPMC-1999-06-0196

A 64-year-old woman with a long history of irritable bowel syndrome.

Poorly differentiated gastric adenocarcinoma with metastatic disease involving the colon arising in a background of chronic active gastritis with incomplete intestinal metaplasia with heavy colonization by Helicobacter pylori.

A2

TS

UPMC-2005-07-0431

A 30 year-old female with multiple gastric polyps.

Fundic gland polyps with focal low-grade dysplasia.

A2

U

UPMC-1995-09-0036

A 70 year-old male with a gastric mass.

Menetrier's disease.

A3

TM

UPMC-2007-04-0505

A 71 year-old male with right flank pain.

Metastatic seminoma in the duodenum.

A3

U

UPMC-2009-08-0616

A 23 year-old male with portal hypertension in the stomach and an erythematous proximal jejunum.

Pseudomelanosis duodeni.

A4

TN

UPMC-2001-01-0255

A 69-year-old male with a history of colonic adenocarcinoma.

Invasive well-differentiated mucin producing adenocarcinoma arising in a small bowel villous adenoma.

A5

TN

UPMC-2008-09-0574

A 68 year-old female with acute appendicitis.

Goblet cell carcinoid.

A6

I

UPMC-2004-06-0391

A male in his 20s with HIV, diarrhea and abdominal pain.

Cytomegalovirus (CMV) colitis, intestinal spirochetosis. infection (CMV colitis)

A6

I

UPMC-1999-04-0189

A 52 year-old woman with gastrointestinal bleeding and a history of rheumatoid arthritis.

Necrotizing leukocytoclastic small vessel vasculitis of the colon, of probable autoimmune etiology.

A6

TN

UPMC-2014-12-0849

A 71 year-old male with a right colonic mass.

Mixed adenoneuroendocrine carcinoma- signet ring type.

A6

TN

UPMC-2014-05-0828

An 83 year-old female with a lower gastrointestinal bleed and multiple lesions.

Mixed neuroendocrine carcinoma of the cecum.

A6

TN

UPMC-2013-03-0770

A 52-year-old male with a 3 week history of abdominal pain.

Leiomyosarcoma, myxoid variant.

A6

TN

UPMC-2008-07-0568

A 53-year-old man with abdominal distention.

Pseudomyxoma peritonei, peritoneal mucinous carcinomatosis of presumed appendiceal origin.

A7

I

UPMC-2009-09-0622

A 35-year-old male with rectal bleeding.

Schistosomiasis.

A7

U

UPMC-2018-05-0991

A 41 year-old male with rectal bleeding.

Brown bowel syndrome

A7

U

UPMC-2017-02-0934

A 58-year-old female with a colonic mass.

Polypoid endometriosis with transmural involvement of rectosigmoid colon. Endometriosis shows foci of simple hyperplasia and mucinous metaplasia.

B0

TC

UPMC-2019-03-1021

A peculiar mucinous tumor of the breast.

Mucinous cystadenocarcinoma of the breast.

B0

TH

UPMC-2006-11-0485

A 65-year-old woman with malignant lymphoma.

Malignant lymphoma, small B-cell type with plasmacytic differentiation and crystal-storing histiocytosis.

B0

TN

UPMC-2019-10-1037

A woman in her 50's with a breast mass.

Malignant adenomyoepithelioma

B0

TN

UPMC-2006-06-0469

A 74-year-old female with a breast mass a breast mass.

Metaplastic carcinoma of the breast, spindle cell type.

B0

TN

UPMC-2001-02-0258

A 71 year-old woman with a mass in left breast.

Carcinosarcoma (high-grade malignant phylloides tumor with high-grade mammary carcinoma).

B0

TN

UPMC-2000-11-0249

A 59-year-old woman with a nodule in the right breast.

Myofibroblastoma, epithelioid type.

B0

TN

UPMC-1998-04-0140

A 54-year-old female with a left breast mass.

Adenoid cystic carcinoma, grade II of III.

B0

TN

UPMC-1997-08-0116

A 42 year-old woman with right breast mass.

Metaplastic carcinoma of the breast, matrix producing type, (poor nuclear grade).

B0

TS

UPMC-2002-12-0331

A 64-year-old female with left nipple discharge and an inverted nipple.

Paget's disease of the breast.

B0

U

UPMC-2003-01-0338

A 43 year-old woman with a palpable breast mass.

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease).

C1

G

UPMC-2006-09-0479

A 4 year-old boy with cardiomyopathy

Desmin cardiomyopathy.

C1

I

UPMC-1998-12-0175

A 72 year-old white female with respiratory distress.

Idiopathic giant cell myocarditis.

C1

U

UPMC-2015-12-0886

A man at 70s had episodes of syncope.

Sarcoidosis involving the myocardial conduction system.

C1

U

UPMC-2011-01-0676

A 73 year-old male had a heart transplant.

Heterotopic breast epithelial inclusion of the heart.

C1

U

UPMC-2000-04-0223

A 37-year-old female with sudden onset of cardiac arrhythmias following a flu-like illness.

Arrhythmogenic right ventricular cardiomyopathy.

C1

U(P)

UPMC-2012-11-0755

An 11 year-old female who collapsed during out-patient clinic visit.

Left ventricular non-compaction.

C2

TN

UPMC-2002-04-0303

A 67 year-old man with progressive shortness of breath.

Rhabdomyosarcoma of pulmonary artery trunk.

D1

C

UPMC-2008-05-0555

A 45 year-old man with a midline tongue lesion.

Foregut duplication cyst of the tongue.

D1

TH

UPMC-2008-04-0553

A 66-year-old male with a history of precursor B-cell acute lymphoblastic leukemia now presents with an upper lip soft tissue mass.

Histiocytic neoplasm, post-acute lymphoblastic leukemia.

D1

TN(P)

UPMC-2018-01-0970

A term female neonate with two oral cavity masses.

Congenital epulis (congenital granular cell tumor)

D2

TN(P)

UPMC-2018-04-0985

A preadolescent male presented to a dental clinic with an asymptomatic swelling in the oral cavity.

Primordial odontogenic tumor with hard tissue formation.

E0

TN

UPMC-2017-05-0943

A woman in her 60s with a parotid mass.

Basal cell adenocarcinoma ex pleomorphic adenoma, tubular, trabecular and cribriform patterns, with oncocytic differentiation.

E0

TN

UPMC-2012-01-0715

A 61 year-old female with a right-sided submandibular gland mass.

Mucoepidermoid carcinoma, high-grade.

E0

TN

UPMC-2001-09-0281

A 53 year-old woman with a parotid gland mass.

Sebaceous lymphadenoma.

E0

TN(P)

UPMC-2017-09-0955

A year-old boy with a parotid lump.

Mammary analogue secretory carcinoma of salivary gland

F0

TN

UPMC-2016-02-0896

A woman in her 50s with severe pain in right lower quadrant and vomiting.

Synchronous endometrioid adenocarcinomas of the endometrium and right ovary associated with extensive endometriosis.

F0

U

UPMC-2017-02-0934

A 58-year-old female with a colonic mass.

Polypoid endometriosis with transmural involvement of rectosigmoid colon. Endometriosis shows foci of simple hyperplasia and mucinous metaplasia.

F0

U

UPMC-2016-02-0896

A woman in her 50s with severe pain in right lower quadrant and vomiting.

Synchronous endometrioid adenocarcinomas of the endometrium and right ovary associated with extensive endometriosis.

F0

U(P)

UPMC-2013-06-0782

A two-year-old male with left undescended

testis.

Persistent Müllerian duct syndrome.

F1

TN

UPMC-2015-04-0863

A female in her 30s with an enlarging left labial mass

Fibroadenoma of the vulva.

F1

TN

UPMC-2008-03-0549

A 35 year-old woman with a vulvar mass

Atypical myxoid tumor: favor atypical myxoid leiomyoma of the vulva.

F2

TN

UPMC-2017-03-0938

Post-menopausal female with bleeding and vaginal bulge.

Leiomyo-adenomatoid tumor

F3

TN

UPMC-1997-04-0100

A 33 year-old woman with post coital bleeding and vaginal discharge.

Poorly differentiated glassy cell carcinoma (adenosquamous) of the uterine cervix.

F4

TN

UPMC-2002-11-0328

A 57-year-old woman with postmenopausal bleeding.

Malignant Müllerian mixed tumor, heterologous type.

F4

TN(P)

UPMC-2016-09-0912

An adolescent female with abdominal fullness and distension.

Based on the morphologic appearance and immunophenotype, this tumor was diagnosed as a leiomyoma.

F4

U(C)

UPMC-2013-05-0778

A 57 year-old postmenopausal woman with spotting and underwent a routine papanicolaou test-pap smear.

Endometrial cells present in a postmenopausal woman.

F6

I

UPMC-2006-10-0481

A 63-year-old woman with brain metastases and diverticulitis.

Bilateral cytomegalovirus (CMV) associated acute oophoritis with cortical necrosis.

F6

TC

UPMC-2012-12-0759

A 65 year-old female with a large solid-cystic adnexal mass.

Moderate to poorly differentiated Sertoli-Leydig cell tumor.

F6

TN

UPMC-2017-11-0959

A post-menopausal female with an ovarian mass.

Clear cell carcinoma of the ovary

F6

TN

UPMC-2017-06-0947

A post-menopausal female with an ovarian mass.

Intermediately differentiated Sertoli-Leydig cell tumor with mucinous adenocarcinoma as heterologous element.

F6

TN

UPMC-2014-06-0829

A 24-year-old female with gradual onset of abdomen pain.

Synovial sarcoma.

F6

TN

UPMC-2010-06-0653

A 47 year-old woman with a thigh mass.

Follicular thyroid carcinoma arising in struma ovarii with metastasis to the thigh.

F6

TN

UPMC-2005-03-0418

A woman in her 40s with an ovarian mass.

Micropapillary carcinoma (non-invasive type) of the ovary associated with a mature cystic teratoma (dermoid cyst).

F6

TN

UPMC-2003-10-0365

A female in her 70s with pelvic masses

Moderately to poorly differentiated non-small cell neuroendocrine carcinoma.

F6

TN(P)

UPMC-2003-07-0356

Adolescents with ovarian masses.

Mixed sex cord/germ cell tumor, gonadoblastoma and germinoma with granulomatous features, immature teratoma with yolk sac tumor.

F6

TN

UPMC-2003-03-0343

Ovarian mass in a woman at her 50s with endometriosis.

Clear cell carcinoma of right ovary with endometrioid and papillary features, sigmoid colon and omentum positive for metastatic carcinoma, right fallopian tube, sigmoid colon, left ovary, and appendix with endometriosis.

F6

TN(P)

UPMC-2001-06-0270

A 15-year-old girl with an ovarian mass.

Sex cord stromal tumor with combined poorly differentiated juvenile granulosa and Sertoli Leydig differentiation, recurrent sex cord stromal tumor with metastatic serosal implantation of sigmoid colon epiploica and omentum.

F6

TN(P)

UPMC-2017-12-0967

A teenage female with an ovarian mass.

Small cell carcinoma of the ovary, hypercalcemic type

F6

TS

UPMC-2004-07-0394

A woman in her 60s with an incidental finding in the left ovary.

Hilus (or Leydig) cell hyperplasia.

F7

U

UPMC-2019-09-1036

A 36-week dichorionic-diamniotic twin placenta.

Multi-cystic placental lesions.

F7

U

UPMC-1998-01-0128

A 36 year-old female with early intrauterine loss of twin B.

Placenta "A": reactive amnion with moderate meconium containing macrophages; Placenta "B": complete hyalinization and loss of fetal vessels.

F7

U(P)

UPMC-2010-07-0655

A still born fetus (32 weeks gestation) from a mother with multiple medical problems.

Intrauterine fetal demise due to multifocal chorangiomatosis of the placenta.

G0

TN

UPMC-2017-01-0927

A woman presented with severe back pain and lytic lesions in lumbar spine and a pelvic mass.

Primitive neuroectodermal tumors/Ewing sarcoma.

G0

U

UPMC-2004-01-0375

A woman in her 40s with endometriosis and bland glandular inclusions.

Endometriosis of ileocecal junction, focal endometriosis in two of seventeen lymph nodes, bland glandular inclusions in two of seventeen lymph nodes.

G0

U(P)

UPMC-2013-06-0782

A two-year-old male with left undescended

testis.

Persistent Müllerian duct syndrome.

G1

G

UPMC-2018-10-1001

Alström syndrome in an adolescent male and a review of the literature.

Mixed germ cell tumor (embryonal carcinoma; yolk sac tumor, post-pubertal type; teratoma, post-pubertal type) with invasion of the rete testis, lymphovascular invasion and germ cell neoplasia in-situ.

G1

G(P)

UPMC-2001-07-0275

A 16 year-old male with a right testicular mass.

Large cell calcifying Sertoli cell tumors, multifocal, Leydig cell hyperplasia (Carney complex).

G1

TC(P)

UPMC-2001-10-0284

A 15 year-old male with a left testicular mass.

Sertoliform cystadenoma of the rete testis.

G1

TN

UPMC-2018-10-1001

Alström syndrome in an adolescent male and a review of the literature.

Mixed germ cell tumor (embryonal carcinoma; yolk sac tumor, post-pubertal type; teratoma, post-pubertal type) with invasion of the rete testis, lymphovascular invasion and germ cell neoplasia in-situ.

G1

TN

UPMC-2006-03-0459

An 80-year-old man with a right paratesticular mass.

Paratesticular angiosarcoma following radiation therapy for prostatic adenocarcinoma.

G1

TN

UPMC-2006-03-0459

An 80-year-old man with a right paratesticular mass.

Paratesticular angiosarcoma following radiation therapy for prostatic adenocarcinoma.

G1

TN

UPMC-2005-09-0438

A 33 year-old male with testicular discomfort.

Papillary cystadenoma of the epididymis.

G1

TN

UPMC-2004-10-0404

A 71 year-old man with a left testicular mass.

Leydig cell tumor.

G1

TN(P)

UPMC-2004-09-0400

An infant with pain over the left scrotum.

Juvenile granulosa cell tumor.

G1

TN(P)

UPMC-2009-11-0631

A 7 month-old baby with an incidental testicular tumor and congenital nephrotic syndrome.

Denys-Drash syndrome. Dysgenetic testis with juvenile granulosa cell tumor. Blastematous Wilms tumor in right kidney, and nephroblastematosis.

G1

TN(P)

UPMC-2001-07-0275

A 16 year-old male with a right testicular mass.

Large cell calcifying Sertoli cell tumors, multifocal, Leydig cell hyperplasia (Carney complex).

G1

U(P)

UPMC-2014-07-0833

A 4 week-old boy with an abdominal mass.

Intratesticular fetus in fetu.

G2

TN

UPMC-2018-03-0981

A middle aged male with a seminal vesicle mass.

High-grade epithelial stromal tumor of the left seminal vesicle.

G2

TN

UPMC-2011-12-0711

A 72 year-old man with elevated PSA.

Prostatic adenocarcinoma with pleomorphic and ductal features, Gleason score 4+5.

G2

TN

UPMC-2010-09-0665

A 68 year-old white male with bladder outlet obstruction.

Poorly differentiated prostatic adenocarcinoma, Gleason 4+5=9 with high-grade prostatic intraepithelial neoplasia and chronic prostatitis.

G2

TN

UPMC-1999-08-0203

An 84 year-old man with bladder outlet obstruction.

Prostatic adenocarcinoma, large duct type (also known as endometrioid adenocarcinoma or ductal adenocarcinoma).

H0

TH

UPMC-2016-10-0916

A man in his 50s with acute onset aphasia and right sided weakness.

Intravascular lymphoma, large B-cell type.

H0

TH

UPMC-2016-04-0902

A 61-year-old female with a mass in the right supraclavicular area.

Non-Hodgkin lymphoma, peripheral T-cell type, with features of ALK-1 negative anaplastic large cell lymphoma.

H0

TH

UPMC-2010-07-0656

A 48 year-old female with persistent fever, fatigue, loss of appetite and weight loss after surgery.

Intravascular lymphomatosis (intravascular lymphoma).

H0

TH

UPMC-2010-03-0644

A 51 year-old female with morbid obesity and abdominal pain, severe constipation and thirst.

B-cell lymphoid neoplasm with high-grade features (abdominal lymphomatosis)

H0

TH

UPMC-2009-05-0605

A 76 year-old woman with a left thigh mass

Primary cutaneous follicle center lymphoma.

H0

TH

UPMC-2008-04-0553

A 66-year-old male with a history of precursor B-cell acute lymphoblastic leukemia now presents with an upper lip soft tissue mass.

Histiocytic neoplasm, post-acute lymphoblastic leukemia.

H0

TH

UPMC-2007-11-0533

A 41 year man with sharp pain in the right side of his rib cage.

Langerhans cell histiocytosis.

H0

TH

UPMC-2006-11-0485

A 65-year-old woman with malignant lymphoma.

Malignant lymphoma, small B-cell type with plasmacytic differentiation and crystal-storing histiocytosis.

H0

TH

UPMC-2004-12-0411

A male in his 60s with plasma cell neoplasm, favor solitary plasmacytoma of bone.

Plasma cell neoplasm, favor solitary plasmacytoma of bone.

H0

TH

UPMC-2003-12-0371

A male in his 30s with a mediastinal mass.

Mediastinal B-cell lymphoma.

H0

TH

UPMC-2002-06-0310

A 51 year-old woman with a nasal mass.

Malignant lymphoma, extranodal NK/T-cell lymphoma, nasal type, most likely of natural killer cell origin.

H0

TH

UPMC-2000-08-0241

A 71 year-old man with acute renal failure.

Waldenstrom's macroglobulinemia with advanced amyloidosis, atypical, monoclonal lymphoplasmacytic interstitial infiltrate with admixed reactive T-lymphocytes; consistent with renal interstitial involvement by lymphoplasmacytic lymphoma.

H0

TH

UPMC-1998-06-0147

A 24 year-old man with end-stage restrictive lung disease and liver disease.

Langerhans Cell Histocytosis.

H0

TH

UPMC-1996-03-0055

A 65 year-old female with right neck mass.

Follicular dendritic cell tumor involving thyroid and right cervical lymph nodes.

H0

TH(C)

UPMC-2003-09-0363

A male in his 80s with left sided neck mass-FNA.

Alk-1 positive anaplastic large cell lymphoma.

H0

TH(P)

UPMC-2010-10-0668

A 6 year-old girl with a large left neck mass.

Post-transplant lymphoproliferative disorder (PTLD) of the Burkitt lymphoma type.

H0

TH(P)

UPMC-2007-06-0513

A 7 year-old boy with multiple skin lesions.

CD30 positive lymphoproliferative disorder of the skin.

H0

TN

UPMC-2013-09-0793

A 69-year-old woman with a groin mass.

Merkel cell carcinoma.

H0

TN

UPMC-2012-06-0734

A 44 year-old female with a splenic mass.

Sclerosing angiomatoid nodular transformation of spleen

H0

U

UPMC-2015-03-0858

A woman in her 70s with a bladder mass.

Clear cell adenocarcinoma associated with nephrogenic adenoma, adenocarcinoma in situ, intestinal metaplasia and lymph node involvement by endosalpingiosis.

H0

U

UPMC-2003-01-0338

A 43 year-old woman with a palpable breast mass.

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease).

H0

U

UPMC-2002-11-0327

A 17 year-old female with left upper neck mass.

Angiofollicular hyperplasia (Castleman's disease), hyaline-vascular type.

H0

U

UPMC-2002-08-0318

A 74-year-old man with a right thigh mass.

Extranodal Rosai-Dorfman disease.

I0

TH

UPMC-2002-06-0310

A 51 year-old woman with a nasal mass.

Malignant lymphoma, extranodal NK/T-cell lymphoma, nasal type, most likely of natural killer cell origin.

I0

TN

UPMC-2002-09-0321

A nasopharyngeal mass in an 87-year-old woman.

Malignant melanoma.

J0

C(P)

UPMC-2013-12-0804

A neonate with spontaneous pneumothorax and progressive respiratory failure.

Alveolar capillary dysplasia with misalignment of pulmonary veins.

J0

F

UPMC-2011-07-0698

A 55 year-old male with recurrent spontaneous pneumothoraces.

Talc granulomatosis due to intravenous drug abuse.

J0

I

UPMC-2010-07-0657

A 25 year-old white male with a history of schizoaffective disorder and difficult breathing.

Staphylococcus aureus pneumonia complicating influenza.

J0

I

UPMC-1999-10-0181

A 39 year-old man with lung abscess.

Severe right lung necrotizing pneumonia with mucormycosis.

J0

I

UPMC-1997-01-0089

A 59 year-old male with lung mass.

Pneumonia associated with Cryptococcus neoformans.

J0

TC(P)

UPMC-2011-04-0687

A newborn with large, thin-walled cysts in the left hemithorax.

Cystic pleuropulmonary blastoma.

J0

TH

UPMC-2002-03-0299

A 46 year-old man with a right lower lobe pulmonary mass.

Primary adenocarcinoma of lung with clear cell features associated with pulmonary Langerhans cell histiocytosis.

J0

TN

UPMC-2018-11-1004

A middle aged female with left lower lobe lung mass.

Sclerosing pneumocytoma

J0

TN

UPMC-2014-10-0842

A 65-year-old female with an incidental lung mass.

Sclerosing hemangioma

J0

TN

UPMC-2013-01-0763

A 66-year-old female with a lung mass.

Pulmonary cavernous hemangioma.

J0

TN

UPMC-2008-06-0559

A 77 year-old man with worsening dyspnea.

Diffusely infiltrating, moderately differentiated left lung primary adenocarcinoma, diffuse interstitial pulmonary fibrosis/usual interstitial pneumonia.

J0

TN

UPMC-2002-03-0299

A 46 year-old man with a right lower lobe pulmonary mass.

Primary adenocarcinoma of lung with clear cell features associated with pulmonary Langerhans cell histiocytosis.

J0

TN

UPMC-2001-04-0265

A 62 year-old woman with back pain.

Invasive poorly differentiated adenocarcinoma of lung with vertebral metastasis.

J0

TN

UPMC-2000-06-0230

A 34 year-old male with a large right lung mass.

Invasive pulmonary thymoma, mixed lymphoepithelial type, with extensive pleural spread.

J0

TN

UPMC-1995-11-0046

A 55 year-old female with hemoptysis.

Well- differentiated fetal type adenocarcinoma associated with angiolymphatic and visceral pleural invasion.

J0

U

UPMC-2015-01-0853

A woman in her 70s with a double lung transplant.

Pulmonary alveolar microlithiasis.

J0

U

UPMC-2008-06-0559

A 77 year-old man with worsening dyspnea.

Diffusely infiltrating, moderately differentiated left lung primary adenocarcinoma, diffuse interstitial pulmonary fibrosis/usual interstitial pneumonia.

J0

U

UPMC-2005-01-0412

A caucasian woman in her late 20s with progressive shortness of breath.

Granulomatous pneumonitis secondary to sarcoidosis.

J0

U(P)

UPMC-2013-12-0804

A neonate with spontaneous pneumothorax and progressive respiratory failure.

Alveolar capillary dysplasia with misalignment of pulmonary veins.

J0

X

UPMC-1998-05-0143

A 35 year-old woman with a history of arthralgia and myalgia.

Mixed connective tissue disease with pulmonary fibrosis, secondary pulmonary hypertension and hyaline membrane disease.

K0

G(P)

UPMC-2009-11-0631

A 7 month-old baby with an incidental testicular tumor and congenital nephrotic syndrome.

Denys-Drash syndrome. Dysgenetic testis with juvenile granulosa cell tumor. Blastematous Wilms tumor in right kidney, and nephroblastematosis.

K0

TN

UPMC-2019-11-1039

A woman in her 70s with a clear cell renal mass.

Clear cell papillary renal cell carcinoma.

K1

G(P)

UPMC-2009-02-0592

A female fetus with bilateral multicystic kidneys.

Fatty acid oxidation disorder, most likely glutaric acidemia type II.

K1

TC

UPMC-2008-02-0548

A 39-year-old female with a complex renal cyst.

Angiomyolipoma with epithelial cysts.

K1

TM

UPMC-2006-08-0476

A 60 year-old woman with breast cancer and a left renal mass.

Conventional (clear) renal cell carcinoma with metastatic breast carcinoma within renal cell carcinoma and within non-neoplastic renal parenchyma.

K1

TN

UPMC-2016-11-0919

A female in her 80s with a renal mass.

Clear cell papillary renal cell carcinoma

K1

TN

UPMC-2012-10-0750

A 52-year-old female with flank pain, hematuria, and cirrhosis.

Collecting duct carcinoma.

K1

TN

UPMC-2011-06-0692

A 51-year-old woman with chronic fatigue and weakness.

Neuroendocrine carcinoma of the kidney.

K1

TN

UPMC-2011-03-0682

A 69 year-old female with a renal mass.

Renal cell carcinoma with features of clear cell papillary subtype.

K1

TN

UPMC-2009-04-0602

A 62 year-old man with an unexplained 60 lb weight loss.

Glomus tumor of the kidney.

K1

TN

UPMC-2008-08-0570

A 69-year-old male with a renal mass.

High-grade neuroendocrine carcinoma.

K1

TN

UPMC-2006-08-0476

A 60 year-old woman with breast cancer and a left renal mass.

Conventional (clear) renal cell carcinoma with metastatic breast carcinoma within renal cell carcinoma and within non-neoplastic renal parenchyma.

K1

TN

UPMC-2003-05-0348

A man in his 70s with nausea and vomiting.

Renal cell carcinoma.

K1

TN

UPMC-2002-12-0333

A 74 year-old man with right flank pain.

Chromophobic renal cell carcinoma.

K1

TN(P)

UPMC-1999-07-0201

A 19 month-old boy with a renal mass.

Clear cell sarcoma of the kidney, stage 3 (renal hilar node involvement).

K1

TN

UPMC-1997-05-0105

A 68 year-old female with a large mass in the right kidney.

Clear cell renal cell carcinoma with multifocal angiomyolipoma with the kidney and perinephric lymph nodes.

K1

TN

UPMC-1995-05-0029

A 69 year-old female with a renal mass.

Clear cell renal cell carcinoma with associated juxtaglomerular tumor. Nodular hyperplasia of the adrenal gland.

K1

TN(P)

UPMC-2009-11-0631

A 7 month-old baby with an incidental testicular tumor and congenital nephrotic syndrome.

Denys-Drash syndrome. Dysgenetic testis with juvenile granulosa cell tumor. Blastematous Wilms tumor in right kidney, and nephroblastematosis.

K2

TN

UPMC-2015-03-0858

A woman in her 70s with a bladder mass.

Clear cell adenocarcinoma associated with nephrogenic adenoma, adenocarcinoma in situ, intestinal metaplasia and lymph node involvement by endosalpingiosis.

K2

TN

UPMC-2013-10-0794

A 34 year-old man with abdominal pain and dysuria.

Urachal adenocarcinoma associated with villous adenoma.

K2

TN

UPMC-2009-07-0615

A 94 year-old man with a bladder mass.

Invasive urothelial carcinoma with predominant sarcomatoid differentiation.

K2

TN

UPMC-2001-05-0267

An 82 year-old woman with right-sided hydronephrosis.

High-grade urothelial carcinoma with plasmacytoid, micropapillary and glandular differentiation.

K2

TS

UPMC-2015-03-0858

A woman in her 70s with a bladder mass.

Clear cell adenocarcinoma associated with nephrogenic adenoma, adenocarcinoma in situ, intestinal metaplasia and lymph node involvement by endosalpingiosis.

K3

G

UPMC-2019-01-1051

A man in his 20s with proteinuria and deafness.

X-linked Alport syndrome

K3

G

UPMC-2010-08-0662

Renal insufficiency in a 68 year-old woman.

Fabry Disease - mosaic pattern.

K3

G

UPMC-2009-06-0610

A 36-year-old female with microalbuminuria.

Renal involvement by Fabry disease.

K3

G

UPMC-1998-03-0137

A 32 year-old male with recurrent fevers of unknown origin.

Fabry's disease.

K3

I

UPMC-2010-11-0671

A 21 year-old male with acute renal failure.

Post-infectious glomerulonephritis with IgA predominance.

K3

I

UPMC-2010-04-0647

A 30-year-old woman with nephrotic syndrome.

Membranoproliferative glomerulonephritis, type-III (Strife variant).

K3

I

UPMC-2009-01-0590

A 42-year-old man with weakness, fatigue and edema of the face and extremities.

Parvovirus B19-related glomerulonephritis.

K3

I

UPMC-2008-11-0582

A 31 year-old male status-post kidney transplant with increased creatinine.

BK virus nephropathy with diffuse tubular basement membrane C4d staining.

K3

I

UPMC-2008-01-0541

A 62 year-old male with flank pain and hematuria.

Diffuse anti-basement membrane antibody glomerulonephritis with cellular crescents.

K3

I

UPMC-1996-05-0061

A 74 year-old man with a history of scleroderma and recent rapidly progressive renal insufficiency.

Immunotactoid glomerulonephritis.

K3

I

UPMC-1996-02-0051

A 73 year-old man with acute renal failure.

Wegener’s granulomatosis.

K3

TH

UPMC-2000-08-0241

A 71 year-old man with acute renal failure.

Waldenstrom's macroglobulinemia with advanced amyloidosis, atypical, monoclonal lymphoplasmacytic interstitial infiltrate with admixed reactive T-lymphocytes; consistent with renal interstitial involvement by lymphoplasmacytic lymphoma.

K3

U

UPMC-2012-02-0717

An 18 year-old male with microscopic hematuria.

Early dense deposit disease (membranoproliferative glomerulonephritis type II)

K3

U

UPMC-2008-11-0582

A 31 year-old male status-post kidney transplant with increased creatinine.

BK virus nephropathy with diffuse tubular basement membrane C4d staining.

K3

U

UPMC-1998-02-0125

A 65 year-old woman with renal insufficiency.

Advanced amyloidosis and chronic secondary ischemia with marked chronicity changes.

K3

U

UPMC-1997-02-0078

A 68 year-old male with renal insufficiency.

Diffuse fibrillary glomerulopathy.

L0

TM

UPMC-2014-09-0838

A 75 year-old male with obstructive jaundice and a pancreatic head mass- with FNA.

Metastatic prostatic adenocarcinoma.

L1

I

UPMC-2019-01-1012

An unusual cause of liver failure leading to liver transplantation.

HAV associated hepatic failure with unusual presentation.

L1

I(C)

UPMC-2002-02-0297

A 35 year-old man with jaundice and weight loss-FNA.

Cholangiocarcinoma, secondary to infection of liver flukes (Clonorchis sinensis or Opisthorchis viverrini).

L1

I(P)

UPMC-2017-04-0940

A post-transplant teenager with liver lesion.

EBV-associated smooth muscle tumor.

L1

T1

UPMC-2006-12-0488

A 72 year-old woman with a history of cirrhosis secondary to alcohol abuse and hepatitis c.

Cholangiocarcinoma arising in a HCV related cirrhotic liver.

L1

TC

UPMC-2010-01-0639

A 61 year-old male with a cystic pancreatic mass.

Cystic schwannoma.

L1

TN(C)

UPMC-2002-02-0297

A 35 year-old man with jaundice and weight loss-FNA.

Cholangiocarcinoma, secondary to infection of liver flukes (Clonorchis sinensis or Opisthorchis viverrini).

L1

TN(C)

UPMC-2012-04-0728

An 81-year-old man with multiple liver masses-FNA.

Metastatic gastrointestinal stromal tumor (GIST), epithelioid type.

L1

TN(C)

UPMC-2011-02-0679

A 10 year-old girl with a hepatic Epstein-Barr virus-associated smooth muscle tumor.

Chronic myelogenous leukemia, chornic phase, BCR-ABL1 positive.

L1

TN(C)

UPMC-2011-02-0679

A 10 year-old girl with a hepatic Epstein-Barr virus-associated smooth muscle tumor.

Chronic myelogenous leukemia, chornic phase, BCR-ABL1 positive.

L1

TN(P)

UPMC-2017-04-0940

A post-transplant teenager with liver lesion.

EBV-associated smooth muscle tumor.

L1

TN(P)

UPMC-2015-07-0875

A 2-year-old girl with a liver mass.

Well-differentiated fetal hepatoblastoma.

L1

TN(P)

UPMC-1998-07-0152

A 2 year-old girl with right upper quadrant mass.

Yolk sac tumor arising in a mature teratoma of the liver.

L1

TS

UPMC-2005-11-0444

A 48-year-old woman with a one-year history of back pain.

Focal nodular hyperplasia lesions of liver.

L3

F

UPMC-2006-01-0451

A 79-year-old male with a lesion in the head of the pancreas.

Post-operative spindle cell nodule, with associated suture granuloma and traumatic neuroma, focal pancreatic intraepithelial neoplasia PanIN II.

L3

I

UPMC-2013-11-0800

Jaundice in a 60 year-old female.

Type 1 autoimmune pancreatitis.

L3

I

UPMC-2010-05-0651

A 67 year-old female with a distal pancreatic mass.

Type 1 autoimmune pancreatitis (IgG4 sclerosing disease).

L3

TN

UPMC-2006-04-0461

A 68-year-old woman with a right parotid mass.

Low-grade cribriform cystadenocarcinoma (aka. "low-grade salivary duct carcinoma")

L3

TN

UPMC-2006-01-0451

A 79-year-old male with a lesion in the head of the pancreas.

Post-operative spindle cell nodule, with associated suture granuloma and traumatic neuroma, focal pancreatic intraepithelial neoplasia PanIN II.

L3

TN

UPMC-2004-04-0384

A man in his 70s with right upper quadrant and left-sided back pain.

Clear cell pancreatic adenocarcinoma.

L3

TN

UPMC-2004-02-0377

A male his 40s with a pancreatic mass.

Acinar cell carcinoma of the pancreas.

L3

TN

UPMC-2003-02-0339

A 56 year-old female with a pancreatic mass.

Pancreatic neuroendocrine carcinoma with solid-pseudopapillary features.

L3

TN

UPMC-1998-11-0172

A 72-year-old man with a distal pancreatic mass.

Pancreatic islet cell tumor.

M0

TC

UPMC-1995-07-0034

A 57 year-old female with an anterior mediastinal mass.

Thymic carcinoid.

M0

TH

UPMC-2003-12-0371

A male in his 30s with a mediastinal mass.

Mediastinal B-cell lymphoma.

N0

F(P)

UPMC-2003-08-0359

A teenager male with a brain mass.

Diffuse large b- cell lymphoma, monomorphic, Post transplantation lymphoproliferative disorder (PTLD).

N0

I

UPMC-2019-12-1041

A woman in her 60's with an abnormal brain MRI an abnormal brain MRI.

Toxoplasmosis

N0

I

UPMC-2003-01-0336

A 38 year-old male with multiple brain masses.

Acute demyelinating disease.

N0

I

UPMC-2001-12-0290

A 58 year-old male with fevers, cutaneous nodules and cerebrovascular accident.

Disseminated Scedosporium prolificans (inflatum) infection.

N0

I

UPMC-1998-08-0156

A 38 year-old kidney transplant patient with progressive mental status change.

Granulomatous amoebic encephalitis due to Acanthamoeba castellanii.

N0

I

UPMC-1996-10-0079

A 44 year-old woman with new brain lesion.

Acute demyelinating lesion consistent with multiple sclerosis.

N0

TC(P)

UPMC-2017-10-0956

A preadolescent female with a series of neurological symptoms.

Neurenteric Cyst

N0

TH

UPMC-2016-10-0916

A man in his 50s with acute onset aphasia and right sided weakness.

Intravascular lymphoma, large B-cell type.

N0

TH

UPMC-1996-12-0088

A 44 year-old HIV positive man died following bleeding from mouth and nose.

Disseminated Mycobacterium avium complex infection, disseminated Klebsiella pneumoniae infection, central nervous system lymphoma and extensive hemorrhage.

N0

TH(P)

UPMC-2003-08-0359

A teenager male with a brain mass.

Diffuse large b- cell lymphoma, monomorphic, Post transplantation lymphoproliferative disorder (PTLD).

N0

TN

UPMC-2014-11-0844

A woman in her 50s with a cervical spinal tumor.

Melanocytoma.

N0

TN

UPMC-2009-10-0626

A 79 year-old female with a cauda equina tumor.

Myxopapillary ependymoma, WHO grade I.

N0

TN

UPMC-2007-08-0523

A 43 year-old man with back pain and a spinal mass.

Paraganglioma with extensive gangliocytic differentiation.

N0

TN

UPMC-2007-07-0521

An 18-year-old female with a brain mass.

Pleomorphic xanthoastrocytoma.

N0

TN

UPMC-2007-02-0497

A 38-year-old man with a nodular brain mass.

Recurrent oligodendroglioma.

N0

TN

UPMC-2006-07-0472

A 57 year-old woman with a cerebellar mass.

Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum).

N0

TN

UPMC-2005-10-0442

A 60-year-old man with a history of headaches.

Calcifying pseudoneoplasm of the neuraxis in association with a ganglioglioma.

N0

TN

UPMC-2003-11-0370

A male in his 70s with a brain mass.

Meningioma, secretory variant.

N0

TN

UPMC-2003-03-0342

A lady in her 20s with a history of upper extremity numbness and weakness.

Hemangioblastoma.

N0

TN

UPMC-2002-10-0324

A 27-year-old female with anaplastic ependymoma.

Anaplastic ependymoma (WHO grade III/IV).

N0

TN

UPMC-1999-12-0212

A 48 year-old woman with new onset diplopia and mental status changes.

Pineoblastoma.

N0

TN(P)

UPMC-1995-01-0011

Posterior fossa mass in a two month-old female.

Polar spongioblastoma with focal pilocytic astrocytoma differentiation. (Note: polar spongioblastoma was included in the WHO 1979 classification but had since been removed. It is not recognized currently as a distinct entity).

N0

TN(C)

UPMC-1999-01-0179

Intraventricaular mass in a 4 year-old girl.

Subependymal giant cell astrocytoma.

N0

TN(P)

UPMC-2012-08-0742

A 13-year-old girl with a history of frequent headaches.

Subependymal giant cell astrocytoma.

N0

U

UPMC-2014-03-0816

A 27-year-old male with deteriorating levels of consciousness.

Acute Wernicke-type encephalopathy

N0

U

UPMC-2005-10-0442

A 60-year-old man with a history of headaches.

Calcifying pseudoneoplasm of the neuraxis in association with a ganglioglioma.

N0

U(P)

UPMC-2005-08-0436

A 13-year-old boy with neurodegeneration.

Neuronal intranuclear inclusion disease, juvenile-sporadic.

N1

I

UPMC-2000-02-0210

A 56 year-old woman with left facial numbness.

Sural nerve:   Axonal degeneration with non-caseating granulomas and vasculitis. Medial gastrocnemius muscle: Granulomatous myositis.

O0

G(P)

UPMC-2004-05-0389

A baby girl with a bulging eye.

Plexiform neurofibroma of the orbit, melanocytic nevus of the iris (lisch nodule), diffuse uveal hamartoma with neural and melanocytic elements, buphthalmos, anterior peripheral synechiae, retinal degeneration affecting predominantly the ganglion cell layer, cupping of the optic nerve head, cataractous lens.

O0

TN(P)

UPMC-2004-05-0389

A baby girl with a bulging eye.

Plexiform neurofibroma of the orbit, melanocytic nevus of the iris (lisch nodule), diffuse uveal hamartoma with neural and melanocytic elements, buphthalmos, anterior peripheral synechiae, retinal degeneration affecting predominantly the ganglion cell layer, cupping of the optic nerve head, cataractous lens.

P0

TH

UPMC-2010-03-0644

A 51 year-old female with morbid obesity and abdominal pain, severe constipation and thirst.

B-cell lymphoid neoplasm with high-grade features (abdominal lymphomatosis)

P0

TN

UPMC-2008-07-0568

A 53-year-old man with abdominal distention.

Pseudomyxoma peritonei, peritoneal mucinous carcinomatosis of presumed appendiceal origin.

P0

TN

UPMC-2000-01-0217

A 55 year-old woman with solitary fibrous tumor of the pleura.

Solitary fibrous tumor (localized fibrous tumor) of the pleura.

Q0

C(P)

UPMC-2008-10-0576

A 13 year-old female with a unilateral neck mass.

Cervical thymic cyst.

R0

TC

UPMC-1999-02-0182

A 31-year-old female with a right upper quadrant cyst.

Vascular adrenal cyst.

R0

TN

UPMC-2003-05-0348

A man in his 70s with nausea and vomiting.

Renal cell carcinoma.

R0

TN

UPMC-2000-09-0244

A 71 year-old woman with an adrenal mass.

Corticomedullary tumor with elements of pheochromocytoma and adrenocortical adenoma.

R0

TN

UPMC-1998-10-0166

A 63 year-old woman with right-sided mass involving kidney and liver.

Adrenal cortical carcinoma with direct extension into the liver.

R0

TN

UPMC-1996-09-0076

Retroperitoneal masses in a 45 year-old man and a 42 year-old woman.

Case 1: Extraadrenal Paraganglioma. Case 2: Malignant Extraadrenal Paraganglioma with metastasis to the lesser curvature of the stomach and one right sacral neural foramina lymph node.

R0

TS

UPMC-1995-05-0029

A 69 year-old female with a renal mass.

Clear cell renal cell carcinoma with associated juxtaglomerular tumor. Nodular hyperplasia of the adrenal gland.

S0

F(P)

UPMC-2006-12-0489

A 20 month-old girl with a left calf mass.

Alveolar rhabdomyosarcoma with treatment-induced cytodifferentiation.

S0

F

UPMC-2006-03-0459

An 80-year-old man with a right paratesticular mass.

Paratesticular angiosarcoma following radiation therapy for prostatic adenocarcinoma.

S0

G

UPMC-1999-09-0205

A 30 year-old female with a painful left index finger.

Intra-osseous and soft tissue granulomatous reaction compatible with gout.

S0

I(C)

UPMC-2011-02-0679

A 10 year-old girl with a hepatic Epstein-Barr virus-associated smooth muscle tumor.

Chronic myelogenous leukemia, chornic phase, BCR-ABL1 positive.

S0

TH

UPMC-2006-11-0485

A 65 year-old woman with malignant lymphoma.

Malignant lymphoma, small B-cell type with plasmacytic differentiation and crystal-storing histiocytosis.

S0

TM

UPMC-2010-06-0653

A 47 year-old woman with a thigh mass.

Follicular thyroid carcinoma arising in struma ovarii with metastasis to the thigh.

S0

TN

UPMC-2019-02-1018

Young male with soft tissue mass of ankle.

Pseudomyogenic hemangioendothelioma.

S0

TN

UPMC-2014-06-0829

A 24 year-old female with gradual onset of abdomen pain.

Synovial sarcoma.

S0

TN

UPMC-2013-03-0770

A 52 year-old male with a 3 week history of abdominal pain.

Leiomyosarcoma, myxoid variant.

S0

TN

UPMC-2012-09-0747

A 42 year-old woman with a posterior knee mass.

High-grade sarcoma with features of myxofibrosarcoma.

S0

TN

UPMC-2012-03-0725

A 52 year-old female with intermittent left facial paresthesia/hyperesthesia and swelling.

Malignant solitary fibrous tumor.

S0

TN

UPMC-2008-12-0586

A 39 year-old female with right forearm lesion.

Neurothekeoma.

S0

TN

UPMC-2007-12-0538

A 57 year-old male with a pelvic mass.

Aggressive angiomyxoma with focal marked vascular smooth muscle proliferation.

S0

TN

UPMC-2007-05-0512

A 17-year-old female with a subcutaneous left thigh mass.

Angiomatoid fibrous histiocytoma.

S0

TN(P)

UPMC-2006-12-0489

A 20-month-old girl with a left calf mass.

Alveolar rhabdomyosarcoma with treatment-induced cytodifferentiation.

S0

TN

UPMC-2004-11-0406

A female in her 30s with a right iliac fossa mass.

High-grade sarcoma, favoring malignant peripheral nerve sheath tumor (MPNST).

S0

TN

UPMC-2003-06-0353

A male in his 20s with multiple "atypical" nevi.

Atypical melanocytic neoplasms of uncertain malignant potential.

S0

TN

UPMC-2002-04-0303

A 67 year-old man with progressive shortness of breath.

Rhabdomyosarcoma of pulmonary artery trunk.

S0

TN

UPMC-2002-01-0292

A 30-year-old male with a mass in the right ischial rectal fossa.

Synovial sarcoma.

S0

TN

UPMC-2000-11-0249

A 59-year-old woman with a nodule in the right breast.

Myofibroblastoma, epithelioid type.

S0

TN

UPMC-2000-10-0346

A 43-year-old obese female with vague left hip discomfort and low back pain.

Primary low-grade leiomyosarcoma of left ilium.

S0

TN(P)

UPMC-1999-07-0201

A 19 month-old boy with a renal mass.

Clear cell sarcoma of the kidney, stage 3 (renal hilar node involvement).

S0

TN

UPMC-1997-10-0121

A 62 year-old man with a left supraclavicular mass.

Palisaded myofibroblastoma (intranodal hemorrhagic spindle-cell tumor with "amianthoid" fibers).

S0

TN

UPMC-1997-07-0107

A 67 year-old female with skin lesion.

Cutaneous leiomyosarcoma.

S0

TN(C)

UPMC-2015-05-0868

A man in his early 20s with a mass on the lateral aspect of his right lower leg-with FNA.

Schwannoma.

S0

TN(P)

UPMC-2013-07-0787

A 7-month-old male with a 4.5 cm deep left inner thigh lesion.

Kaposiform hemangioendothelioma.

S0

U

UPMC-2002-08-0318

A 74-year-old man with a right thigh mass.

Extranodal Rosai-Dorfman disease.

S0

U

UPMC-2001-08-0277

A 44 year-old white male with a left flank mass.

Diffuse angiomatosis (angiomatosis of soft tissue, diffuse hemangioma).

S0

U(P)

UPMC-1996-08-0072

A 9½  year-old boy with pain in left proximal medial thigh.

Myositis ossificans.

T1

C(P)

UPMC-2005-05-0425

A 14 year-old boy with congenital hypothyroidism.

Dyshormonogenetic goiter.

T1

I

UPMC-2005-02-0415

A female in her 20s with a thyroid mass.

Papillary thyroid carcinoma, diffusely involving both thyroid lobes, background thyroid with severe chronic lymphocytic thyroiditis in a follicular destructive pattern.

T1

TH

UPMC-2005-02-0415

A female in her 20s with a thyroid mass.

Papillary thyroid carcinoma, diffusely involving both thyroid lobes, background thyroid with severe chronic lymphocytic thyroiditis in a follicular destructive pattern.

T1

TH

UPMC-1996-03-0055

A 65 year-old female with right neck mass.

Follicular dendritic cell tumor involving thyroid and right cervical lymph nodes.

T1

TM

UPMC-2006-02-0454

65 year-old man with an enlarged thyroid-FNA.

Metastatic renal cell carcinoma.

T1

TN

UPMC-2013-04-0777

A 57 year-old female with an actively growing right neck mass.

Anaplastic thyroid carcinoma.

T1

TN

UPMC-2006-05-0465

A 69-year-old man presented with a left neck mass.

Papillary carcinoma, hyalinizing trabecular tumor, multinodular thyroid.

T1

TN

UPMC-2006-05-0466

A 68 year-old female with an incidental thyroid cyst.

Rhabdoid (anaplastic) thyroid carcinoma associated with and/or arising from a papillary thyroid carcinoma.

T1

TN

UPMC-2001-03-0261

A 66 year-old male with a left thyroid mass.

Moderately differentiated medullary carcinoma of the thyroid.

T1

TN

UPMC-1995-12-0045

A 55 year-old male with neck mass.

Well differentiated Hürthle cell carcinoma with focal degeneration.

T1

TN

UPMC-1995-03-0024

An 80 year-old female with a neck mass.

Poorly differentiated "insular" thyroid carcinoma.

T1

TN(C)

UPMC-2014-01-0808

A 58 year-old woman with a thyroid nodule-with FNA.

Suspicious for non-Hodgkin Lymphoma.

U0

TH

UPMC-2011-08-0701

A 49 year-old male with headache and diplopia.

Plasma cell neoplasm - kappa light chain restricted.

U0

TN

UPMC-2005-04-0422

A man in his 20s with a sudden onset of polydipsia and polyuria.

Germinoma.

V0

I

UPMC-2000-02-0210

A 56 year-old woman with left facial numbness.

Sural nerve:   Axonal degeneration with non-caseating granulomas and vasculitis. Medial gastrocnemius muscle: Granulomatous myositis.

V0

I

UPMC-1999-04-0189

A 52 year-old woman with gastrointestinal bleeding and a history of rheumatoid arthritis.

Necrotizing leukocytoclastic small vessel vasculitis of the colon, of probable autoimmune etiology.

V0

I

UPMC-1996-02-0051

A 73 year-old man with acute renal failure.

Wegener’s granulomatosis.

W0

G

UPMC-2009-03-0598

An 87-year-old male with a pathologic hip fracture.

Paget’s disease of bone associated with secondary osteosarcoma of femur invading surrounding soft tissue.

W0

G

UPMC-1999-09-0205

A 30 year-old female with a painful left index finger.

Intra-osseous and soft tissue granulomatous reaction compatible with gout.

W0

G(P)

UPMC-2011-10-0706

A 17 weeks fetus with significant shortening of long bones.

Osteogenesis imperfecta Type II (OI II).

W0

TH

UPMC-2007-11-0533

A 41 year man with sharp pain in the right side of his rib cage.

Langerhans cell histiocytosis.

W0

TH

UPMC-2004-12-0411

A male in his 60s with plasma cell neoplasm, favor solitary plasmacytoma of bone.

Plasma cell neoplasm, favor solitary plasmacytoma of bone.

W0

TM

UPMC-2019-05-1028

Adult male with a lytic temporal bone lesion.

Metastatic acinic cell carcinoma from salivary gland with high-grade transformation

W0

TM

UPMC-2017-01-0927

A woman presented with severe back pain and lytic lesions in lumbar spine and a pelvic mass.

Primitive neuroectodermal tumors/Ewing sarcoma.

W0

TM

UPMC-2010-02-0642

A 75 year-old female with a history of treated urothelial carcinoma.

Metastatic urothelial carcinoma to the calcaneus.

W0

TN

UPMC-2018-02-0975

Middle age female with a femur lesion.

Liposclerosing myxofibrous tumor

W0

TN

UPMC-2013-02-0766

An 80 year-old man with a palpable groin mass.

Dedifferentiated chondrosarcoma.

W0

TN

UPMC-2011-05-0689

An 86 year-old woman with a sacrococcygeal mass-FNA.

Chordoma.

W0

TN

UPMC-2009-03-0598

An 87-year-old male with a pathologic hip fracture.

Paget’s disease of bone associated with secondary osteosarcoma of femur invading surrounding soft tissue.

W0

TN

UPMC-2000-10-0346

A 43-year-old obese female with vague left hip discomfort and low back pain.

Primary low-grade leiomyosarcoma of left ilium.

W0

TN

UPMC-1997-11-0103

A 19 year-old man with progressive low back pain.

Ewing sarcoma, PNET.

W0

TN

UPMC-1997-09-0118

A 67 year-old man with a lytic and blastic lesion of left tibia.

Dedifferentiated chondrosarcoma.

W0

TN

UPMC-1996-06-0064

A 60 year-old man with coccygeal mass.

Chordoma with focal chondroid features.

W0

TN

UPMC-1996-01-0052

A 20 month-old old male with left paravertebral mass.

Yolk sac tumor.

X0

G(P)

UPMC-2007-01-0493

5-month-old twins with turricephaly.

Peroxisome biogenesis disorder, clinically consistent with Zellweger syndrome.

X0

G(P)

UPMC-1997-12-0127

A 24-day-old term infant with seizures.

DiGeorge syndrome, transfusion related graft versus host disease, and multiorgan failure with disseminated intravascular coagulation.

X0

I

UPMC-1998-09-0160

A 35 year-old transplant recipient with fevers and mental status changes.

Disseminated toxoplasmosis.

X0

I

UPMC-1996-12-0088

A 44 year-old HIV positive man died following bleeding from mouth and nose.

Disseminated Mycobacterium avium complex infection, disseminated Klebsiella pneumoniae infection, central nervous system lymphoma and extensive hemorrhage.

X0

I(P)

UPMC-1996-04-0054

Complete heart block in a 9 year-old boy status post small bowel and kidney transplants.

Disseminated fungal sepsis.

X0

TH

UPMC-1998-06-0147

A 24 year-old man with end-stage restrictive lung disease and liver disease.

Langerhans Cell Histocytosis.

X0

TM

UPMC-2004-08-0398

A transplant patient with multiple cutaneous malignancies and related fatal outcome.

Merkel cell carcinoma with metastases to liver, skin, bone marrow of rib, mesenteric lymph nodes, diaphragm, pancreas, and adrenal gland.

X0

TM

UPMC-2003-03-0343

Ovarian mass in a woman at her 50s with endometriosis.

Clear cell carcinoma of right ovary with endometrioid and papillary features, sigmoid colon and omentum positive for metastatic carcinoma, right fallopian tube, sigmoid colon, left ovary, and appendix with endometriosis.

X0

TM

UPMC-1996-09-0076

Retroperitoneal masses in a 45 year-old man and a 42 year-old woman.

Case 1: Extraadrenal Paraganglioma. Case 2: Malignant Extraadrenal Paraganglioma with metastasis to the lesser curvature of the stomach and one right sacral neural foramina lymph node.

X0

TN

UPMC-2000-12-0252

A 75-year-old male with abdominal distension, weakness and anemia.

Sarcoma, suspect recurrent malignant gastrointestinal stromal tumor with extensive peritoneal metastases.

X0

U

UPMC-2000-07-0239

A 24-year-old man with flu-like symptoms.

Polyglandular autoimmune syndrome type II (Schmidt syndrome).

X0

X

UPMC-1998-05-0143

A 35 year-old woman with a history of arthralgia and myalgia.

Mixed connective tissue disease with pulmonary fibrosis, secondary pulmonary hypertension and hyaline membrane disease.

Z0

G

UPMC-1997-06-0109

A 42 year-old male with nevoid basal cell carcinoma syndrome.

Nevoid basal cell carcinoma syndrome (Gorlin syndrome).

Z0

G

UPMC-1996-07-0070

A 38 year-old female with phrynoderma following gastric bypass surgery.

Focal parakeratosis consistent with phrynoderma (vitamin a deficiency).

Z0

G(P)

UPMC-2012-07-0736

Abdominal skin lesion and mass in a newborn.

Neurocutaneous melanocytosis, with a giant congenital melanocytic nevus with neurotization, and a deep proliferative nodule.

Z0

I

UPMC-2011-11-0707

A 53-year-old male with a five-day history of worsening rash, pain and swelling in his right hand.

Neutrophilic dermatosis.

Z0

I

UPMC-2000-03-0219

A 67 year-old post-transplant patient with cutaneous nodules and ulcers.

Necrotizing granulomatous dermatitis, secondary to Scedosporium apiospermum.

Z0

TC

UPMC-2010-12-0674

A 53 year-old man presented with a cyst on his left cheek.

Steatocystoma.

Z0

TH

UPMC-2016-04-0902

A 61-year-old female with a mass in the right supraclavicular area.

Non-Hodgkin lymphoma, peripheral T-cell type, with features of ALK-1 negative anaplastic large cell lymphoma.

Z0

TH

UPMC-2009-05-0605

A 76 year-old woman with a left thigh mass

Primary cutaneous follicle center lymphoma.

Z0

TH

UPMC-2005-06-0429

A 74 year-old female with inflamed "seborrheic keratosis" on dorsum of right ankle.

Malignant melanoma, in situ and invasive.

Z0

TH(P)

UPMC-2007-06-0513

A 7 year-old boy with multiple skin lesions.

CD30 positive lymphoproliferative disorder of the skin.

Z0

TN(P)

UPMC-2018-12-1008

A teenager female with a neck mass.

Eccrine spiradenoma

Z0

TN

UPMC-2015-02-0857

A 70 year-old male with a mass on the right thigh.

Pilomatrix carcinoma of the skin and soft tissue arising on the right thigh with metastases to three right groin lymph nodes.

Z0

TN

UPMC-2013-09-0793

A 69-year-old woman with a groin mass.

Merkel cell carcinoma.

Z0

TN

UPMC-2008-12-0586

A 39 year-old female with right forearm lesion.

Neurothekeoma.

Z0

TN

UPMC-2005-12-0449

An elderly man with a plaque-like crusted lesion of his right temple.

Cutaneous neuroendocrine carcinoma (Merkel cell carcinoma) arising in association with basal cell carcinoma and squamous cell carcinoma in-situ of skin with metastasis to supraclavicular lymph nodes involved by chronic lymphocytic leukemia/small lymphocytic lymphoma.

Z0

TN

UPMC-2004-02-0378

A young woman with an unusual "cyst".

Atypical spindle cell neoplasm, compatible with malignant melanoma, desmoplastic / neurotropic type.

Z0

TN

UPMC-1997-07-0107

A 67 year-old female with skin lesion.

Cutaneous leiomyosarcoma.

Z0

TN

UPMC-1997-06-0109

A 42 year-old male with nevoid basal cell carcinoma syndrome.

Nevoid basal cell carcinoma syndrome (Gorlin syndrome).

Z0

TN

UPMC-1997-03-0097

A 69 year-old male with pigmented lesion on his right ear.

Lentigo maligna (Atypical Lentiginous Hyperplasia).

Z0

TN

UPMC-1995-10-0042

A 54 year-old male with a right cheek mass.

Squamous cell carcinoma.

Z0

TN

UPMC-1995-06-0032

A 79 year-old male with frontal headaches.

Coexistent inverted papilloma and verrucous carcinoma.

Z0

TN(P)

UPMC-2012-07-0736

Abdominal skin lesion and mass in a newborn.

Neurocutaneous melanocytosis, with a giant congenital melanocytic nevus with neurotization, and a deep proliferative nodule.

Z0

TS

UPMC-2005-06-0429

A 74 year-old female with inflamed "seborrheic keratosis" on dorsum of right ankle.

Malignant melanoma, in situ and invasive.

Z0

TS

UPMC-2002-12-0331

A 64-year-old female with left nipple discharge and an inverted nipple.

Paget's disease of the breast.

Z0

U(P)

UPMC-1996-11-0082

A 2 year-old girl with skin lesion on right arm.

Juvenile xanthogranuloma.