Willard Freeman, PhD
- Research Program: Geroscience
- Position: College of Medicine, Department of Biochemistry, Adjunct Professor
Biography
Dr. Freeman is originally from Virginia and completed his undergraduate degrees in Chemistry and English and his PhD in Pharmacology at Wake Forest University in Winston-Salem, North Carolina. After post-doctoral training at the Vollum Institute at Oregon Health & Science University and Yerkes National Primate Research Center at Emory University, Dr. Freeman began his faculty career at the Penn State College of Medicine where he was Assistant and Associate Professor of Pharmacology and Director of the Genome Sciences Facility. Dr. Freeman came to OUHSC in 2013 as a Donald W. Reynolds Chair in Aging Research and become dual-appointed with the Oklahoma City Veterans Affairs Medical Center in 2018. In 2019 Dr. Freeman moved to the Oklahoma Medical Research Foundation as a Member in the Genes & Human Disease Program.
Publications
- Graduate School
-
Molecular Neuroscience
Yerkes National Primate Research Center
Atlanta, GA -
Molecular Neuroscience
Vollum Institute
Portland, OR -
Pharmacology
Wake Forest University School of Medicine
Winston-Salem, NC
- Undergraduate School
-
Chemistry & English
Wake Forest University
Winston-Salem, NC
- Epigenomics of Brain Aging
- Sex differences in Genomic Regulation
- Neuroinflammatory mechanisms of Brain Aging and Neurodegeneration
- Retinal Aging
- Sequencing Technology and Machine Learning Tool Development
- Cellular hallmarks of aging emerge in the ovary prior to primordial follicle depletion 2021
- Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia 2020
- Health benefits attributed to 17a-estradiol, a lifespan-extending compound, are mediated through estrogen receptor a 2020
- Early life DNA methylation profiles are indicative of age-related transcriptome changes 2019
- Caloric-restriction mitigates age-associated alteration in CG and non-CG methylation in the old brain 2018
- Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging 2017
- Sexually divergent DNA methylation patterns with hippocampal aging 2017
- Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice 2016
- Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation 2016
- Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing 2013